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The Characteristics of Patients Frequently Tested and Repeatedly Infected with Neisseria gonorrhoeae

We assessed whether patients repeatedly infected with Neisseria gonorrhoeae (NG) were different compared to patients repeatedly tested negative, to obtain insight into the characteristics of patients frequently tested and infected with NG. All patients tested for NG (n = 16,662) between January 2011...

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Autores principales: Wijers, Juliën, Hoebe, Christian, Dukers-Muijrers, Nicole, Wolffs, Petra, van Liere, Geneviève
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084364/
https://www.ncbi.nlm.nih.gov/pubmed/32110902
http://dx.doi.org/10.3390/ijerph17051495
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author Wijers, Juliën
Hoebe, Christian
Dukers-Muijrers, Nicole
Wolffs, Petra
van Liere, Geneviève
author_facet Wijers, Juliën
Hoebe, Christian
Dukers-Muijrers, Nicole
Wolffs, Petra
van Liere, Geneviève
author_sort Wijers, Juliën
collection PubMed
description We assessed whether patients repeatedly infected with Neisseria gonorrhoeae (NG) were different compared to patients repeatedly tested negative, to obtain insight into the characteristics of patients frequently tested and infected with NG. All patients tested for NG (n = 16,662) between January 2011 and July 2018 were included. Multivariable logistic regression analyses were performed for the outcomes “repeat NG infections” and “once NG positive and not retested” versus patients “repeatedly tested NG negative”. Of the individuals tested for NG, 0.2% (40/16,662) had repeat (≥2) NG infections, and accounted for 23% of all diagnosed NG infections. STI clinic patients, men (mostly men who have sex with men (MSM)), patients aged ≥25 years, and patients co-infected with HIV or Chlamydia trachomatis (CT) more often had repeat NG infections. The number of patients not retested after their initial NG diagnosis was 29.9% (92/308). Men (mostly MSM), HIV positive patients, and patients notified for sexually transmitted infections (STIs) were more often NG positive and not retested. Concluding, only 40 patients tested for NG accounted for one in four diagnosed NG infections. However, re-infections are likely to be missed among MSM and HIV positive patients, as they were mainly not retested after NG infection. It remains important to test and re-test for NG, especially in MSM, in order to halt transmission.
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spelling pubmed-70843642020-03-24 The Characteristics of Patients Frequently Tested and Repeatedly Infected with Neisseria gonorrhoeae Wijers, Juliën Hoebe, Christian Dukers-Muijrers, Nicole Wolffs, Petra van Liere, Geneviève Int J Environ Res Public Health Article We assessed whether patients repeatedly infected with Neisseria gonorrhoeae (NG) were different compared to patients repeatedly tested negative, to obtain insight into the characteristics of patients frequently tested and infected with NG. All patients tested for NG (n = 16,662) between January 2011 and July 2018 were included. Multivariable logistic regression analyses were performed for the outcomes “repeat NG infections” and “once NG positive and not retested” versus patients “repeatedly tested NG negative”. Of the individuals tested for NG, 0.2% (40/16,662) had repeat (≥2) NG infections, and accounted for 23% of all diagnosed NG infections. STI clinic patients, men (mostly men who have sex with men (MSM)), patients aged ≥25 years, and patients co-infected with HIV or Chlamydia trachomatis (CT) more often had repeat NG infections. The number of patients not retested after their initial NG diagnosis was 29.9% (92/308). Men (mostly MSM), HIV positive patients, and patients notified for sexually transmitted infections (STIs) were more often NG positive and not retested. Concluding, only 40 patients tested for NG accounted for one in four diagnosed NG infections. However, re-infections are likely to be missed among MSM and HIV positive patients, as they were mainly not retested after NG infection. It remains important to test and re-test for NG, especially in MSM, in order to halt transmission. MDPI 2020-02-26 2020-03 /pmc/articles/PMC7084364/ /pubmed/32110902 http://dx.doi.org/10.3390/ijerph17051495 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wijers, Juliën
Hoebe, Christian
Dukers-Muijrers, Nicole
Wolffs, Petra
van Liere, Geneviève
The Characteristics of Patients Frequently Tested and Repeatedly Infected with Neisseria gonorrhoeae
title The Characteristics of Patients Frequently Tested and Repeatedly Infected with Neisseria gonorrhoeae
title_full The Characteristics of Patients Frequently Tested and Repeatedly Infected with Neisseria gonorrhoeae
title_fullStr The Characteristics of Patients Frequently Tested and Repeatedly Infected with Neisseria gonorrhoeae
title_full_unstemmed The Characteristics of Patients Frequently Tested and Repeatedly Infected with Neisseria gonorrhoeae
title_short The Characteristics of Patients Frequently Tested and Repeatedly Infected with Neisseria gonorrhoeae
title_sort characteristics of patients frequently tested and repeatedly infected with neisseria gonorrhoeae
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084364/
https://www.ncbi.nlm.nih.gov/pubmed/32110902
http://dx.doi.org/10.3390/ijerph17051495
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