Assessment of the Effect of Sorafenib on Omega-6 and Omega-3 Epoxyeicosanoid Formation in Patients with Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is a leading cause of cancer death. The multikinase inhibitor sorafenib is widely used for systemic therapy in advanced HCC. Sorafenib might affect epoxyeicosanoids, as it is also a potent inhibitor of the soluble epoxide hydrolase (sEH), which catalyzes the conversion...

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Detalles Bibliográficos
Autores principales: Leineweber, Can G., Pietzner, Anne, Zhang, Ingrid W., Blessin, Usha B., Rothe, Michael, Schott, Eckart, Schebb, Nils H., Weylandt, Karsten H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084535/
https://www.ncbi.nlm.nih.gov/pubmed/32182938
http://dx.doi.org/10.3390/ijms21051875

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