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Loss of Histone Locus Bodies in the Mature Hemocytes of Larval Lymph Gland Result in Hyperplasia of the Tissue in mxc Mutants of Drosophila

Mutations in the multi sex combs (mxc) gene in Drosophila results in malignant hyperplasia in larval hematopoietic tissues, called lymph glands (LG). mxc encodes a component of the histone locus body (HLB) that is essential for cell cycle-dependent transcription and processing of histone mRNAs. The...

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Detalles Bibliográficos
Autores principales: Kurihara, Masanori, Komatsu, Kouyou, Awane, Rie, Inoue, Yoshihiro H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084650/
https://www.ncbi.nlm.nih.gov/pubmed/32111032
http://dx.doi.org/10.3390/ijms21051586