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Tuberous Sclerosis Complex Axis Controls Renal Extracellular Vesicle Production and Protein Content

The tuberous sclerosis complex (Tsc) proteins regulate the conserved mTORC1 growth regulation pathway. We identified that loss of the Tsc2 gene in mouse inner medullary collecting duct (mIMCD) cells induced a greater than two-fold increase in extracellular vesicle (EV) production compared to the sam...

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Detalles Bibliográficos
Autores principales:	Zadjali, Fahad, Kumar, Prashant, Yao, Ying, Johnson, Daniel, Astrinidis, Aristotelis, Vogel, Peter, Gross, Kenneth W., Bissler, John J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084746/ https://www.ncbi.nlm.nih.gov/pubmed/32138326 http://dx.doi.org/10.3390/ijms21051729

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