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Systems Biology Analysis Reveals Eight SLC22 Transporter Subgroups, Including OATs, OCTs, and OCTNs

The SLC22 family of OATs, OCTs, and OCTNs is emerging as a central hub of endogenous physiology. Despite often being referred to as “drug” transporters, they facilitate the movement of metabolites and key signaling molecules. An in-depth reanalysis supports a reassignment of these proteins into eigh...

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Detalles Bibliográficos
Autores principales: Engelhart, Darcy C., Granados, Jeffry C., Shi, Da, Saier, Milton H., Baker, Michael E., Abagyan, Ruben, Nigam, Sanjay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084758/
https://www.ncbi.nlm.nih.gov/pubmed/32150922
http://dx.doi.org/10.3390/ijms21051791