Dysregulated Gut Homeostasis Observed Prior to the Accumulation of the Brain Amyloid-β in Tg2576 Mice

Amyloid plaques in Alzheimer’s disease (AD) are associated with inflammation. Recent studies demonstrated the involvement of the gut in cerebral amyloid-beta (Aβ) pathogenesis; however, the mechanisms are still not well understood. We hypothesize that the gut bears the Aβ burden prior to brain, high...

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Detalles Bibliográficos
Autores principales: Honarpisheh, Pedram, Reynolds, Caroline R., Blasco Conesa, Maria P., Moruno Manchon, Jose F., Putluri, Nagireddy, Bhattacharjee, Meenakshi B., Urayama, Akihiko, McCullough, Louise D., Ganesh, Bhanu P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084806/
https://www.ncbi.nlm.nih.gov/pubmed/32138161
http://dx.doi.org/10.3390/ijms21051711

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