Novel HSP90-PI3K Dual Inhibitor Suppresses Melanoma Cell Proliferation by Interfering with HSP90-EGFR Interaction and Downstream Signaling Pathways

Melanoma is the deadliest form of skin cancer, and its incidence has continuously increased over the past 20 years. Therefore, the discovery of a novel targeted therapeutic strategy for melanoma is urgently needed. In our study, MTT-based cell proliferation assay, cell cycle, and apoptosis assays th...

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Detalles Bibliográficos
Autores principales: Zhao, Qian, Zhu, Hong-Ping, Xie, Xin, Mao, Qing, Liu, Yan-Qing, He, Xiang-Hong, Peng, Cheng, Jiang, Qing-Lin, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084941/
https://www.ncbi.nlm.nih.gov/pubmed/32156008
http://dx.doi.org/10.3390/ijms21051845

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