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Production of drug metabolites by human FMO3 in Escherichia coli

BACKGROUND: In the course of drug discovery and development process, sufficient reference standards of drug metabolites are required, especially for preclinical/clinical or new therapeutic drugs. Whole-cell synthesis of drug metabolites is of great interest due to its low cost, low environmental imp...

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Detalles Bibliográficos
Autores principales: Catucci, Gianluca, Gilardi, Gianfranco, Sadeghi, Sheila J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085137/
https://www.ncbi.nlm.nih.gov/pubmed/32197603
http://dx.doi.org/10.1186/s12934-020-01332-1