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Synthesis of acridone derivatives via heterologous expression of a plant type III polyketide synthase in Escherichia coli

BACKGROUND: Acridone alkaloids are heterocyclic compounds that exhibit a broad-range of pharmaceutical and chemotherapeutic activities, including anticancer, antiviral, anti-inflammatory, antimalarial, and antimicrobial effects. Certain plant species such as Citrus microcarpa, Ruta graveolens, and T...

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Detalles Bibliográficos
Autores principales: Choi, Gyu-Sik, Choo, Hye Jeong, Kim, Bong-Gyu, Ahn, Joong-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085191/
https://www.ncbi.nlm.nih.gov/pubmed/32197639
http://dx.doi.org/10.1186/s12934-020-01331-2