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Synthesis of acridone derivatives via heterologous expression of a plant type III polyketide synthase in Escherichia coli
BACKGROUND: Acridone alkaloids are heterocyclic compounds that exhibit a broad-range of pharmaceutical and chemotherapeutic activities, including anticancer, antiviral, anti-inflammatory, antimalarial, and antimicrobial effects. Certain plant species such as Citrus microcarpa, Ruta graveolens, and T...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085191/ https://www.ncbi.nlm.nih.gov/pubmed/32197639 http://dx.doi.org/10.1186/s12934-020-01331-2 |