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Phosphoinositide specific phospholipase Cγ1 inhibition-driven autophagy caused cell death in human lung adenocarcinoma A549 cells in vivo and in vitro

Our previous studies indicated that phosphoinositide specific phospholipase Cγ1 (PLCγ1) was involved in autophagy induction in colon and hepatic carcinoma cells. However, whether and how PLCγ1 regulation in human lung adenocarcinoma is linked to autophagy remains unclear. Here, we assessed the prote...

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Detalles Bibliográficos
Autores principales: Lu, Xiaohong, Fu, Haijing, Chen, Rui, Wang, Yue, Zhan, Yanyan, Song, Gang, Hu, Tianhui, Xia, Chun, Tian, Xuemei, Zhang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085223/
https://www.ncbi.nlm.nih.gov/pubmed/32210730
http://dx.doi.org/10.7150/ijbs.42962

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