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Selective targeting of the TLR4 co-receptor, MD2, prevents colon cancer growth and lung metastasis

Toll-like receptor (TLR) signaling is an emerging pathway in tumor cell invasion and metastasis. Myeloid differentiation protein-2 (MD2) contributes to ligand recognition and activation of TLRs in response to exogenous microbial insults or endogenous agents. We hypothesized that blocking MD2 using a...

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Detalles Bibliográficos
Autores principales:	Rajamanickam, Vinothkumar, Yan, Tao, Xu, Shanmei, Hui, Junguo, Xu, Xiaohong, Ren, Luqing, Liu, Zhoudi, Liang, Guang, Wang, Ouchen, Wang, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085228/ https://www.ncbi.nlm.nih.gov/pubmed/32210720 http://dx.doi.org/10.7150/ijbs.39098

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