Cargando…

ALDH 2 conferred neuroprotection on cerebral ischemic injury by alleviating mitochondria-related apoptosis through JNK/caspase-3 signing pathway

Past studies have indicated that the dysregulation of Aldehyde dehydrogenase 2 (ALDH2) is related to the pathogenesis of acute stroke. However, the underlying mechanisms of ALDH2-mediated acute stroke are still not well understood. Thus, our study was designed to explore the influence of ALDH2 in ac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xia, Pingping, Zhang, Fan, Yuan, Yajing, Chen, Cheng, Huang, Yan, Li, Longyan, Wang, E, Guo, Qulian, Ye, Zhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085232/ https://www.ncbi.nlm.nih.gov/pubmed/32210721 http://dx.doi.org/10.7150/ijbs.38962

Ejemplares similares

MicroRNA-378 Alleviates Cerebral Ischemic Injury by Negatively Regulating Apoptosis Executioner Caspase-3
por: Zhang, Nan, et al.
Publicado: (2016)

TAT-PEP Alleviated Cognitive Impairment by Alleviating Neuronal Mitochondria Damage and Apoptosis After Cerebral Ischemic Reperfusion Injury
por: Zhao, Pin, et al.
Publicado: (2023)

Apoptosis induction in BEFV-infected Vero and MDBK cells through Src-dependent JNK activation regulates caspase-3 and mitochondria pathways
por: Chen, Chun-Yen, et al.
Publicado: (2009)

Polyphenols Mediate Neuroprotection in Cerebral Ischemic Stroke—An Update
por: Abdelsalam, Salaheldin Abdelraouf, et al.
Publicado: (2023)

Modulation of iridovirus-induced apoptosis by endocytosis, early expression, JNK, and apical caspase
por: Chitnis, Nilesh S., et al.
Publicado: (2008)

Tau and Caspase 3 as Targets for Neuroprotection
por: Idan-Feldman, Anat, et al.
Publicado: (2012)

Neuroprotective Effects of the Lithium Salt of a Novel JNK Inhibitor in an Animal Model of Cerebral Ischemia–Reperfusion
por: Schepetkin, Igor A., et al.
Publicado: (2022)

Smurf2 exerts neuroprotective effects on cerebral ischemic injury
por: Liu, Haibin, et al.
Publicado: (2021)

Stroke Neuroprotection: Targeting Mitochondria
por: Talley Watts, Lora, et al.
Publicado: (2013)

PAK-2 Targeting to Mitochondria and Cleavage by Caspases Induces Apoptosis
por: Rudel, Thomas, et al.
Publicado: (2001)

p-Hydroxybenzyl Alcohol Antagonized the ROS-Dependent JNK/Jun/Caspase-3 Pathway to Produce Neuroprotection in a Cellular Model of Parkinson’s Disease
por: Lai, Mei-Chou, et al.
Publicado: (2022)

Isoflurane Preconditioning Confers Cardioprotection by Activation of ALDH2
por: Lang, Xiao-E, et al.
Publicado: (2013)

Astragalus injection protects cerebral ischemic injury by inhibiting neuronal apoptosis and the expression of JNK3 after cerebral ischemia reperfusion in rats
por: Liu, Guangyi, et al.
Publicado: (2013)

Long noncoding RNA Meg3 mediates ferroptosis induced by oxygen and glucose deprivation combined with hyperglycemia in rat brain microvascular endothelial cells, through modulating the p53/GPX4 axis
por: Chen, Cheng, et al.
Publicado: (2021)

The Role of TRPC6 in the Neuroprotection of Calycosin Against Cerebral Ischemic Injury
por: Guo, Chao, et al.
Publicado: (2017)

Piperine as a neuroprotective functional component in rats with cerebral ischemic injury
por: Hua, Shiyao, et al.
Publicado: (2019)

JNK1/2 regulate Bid by direct phosphorylation at Thr59 in response to ALDH1L1
por: Prakasam, A, et al.
Publicado: (2014)

Si-Wu-Tang Alleviates Nonalcoholic Fatty Liver Disease via Blocking TLR4-JNK and Caspase-8-GSDMD Signaling Pathways
por: Zhang, Yaxing, et al.
Publicado: (2020)

Peroxiredoxin 1 alleviates oxygen-glucose deprivation/ reoxygenation injury in N2a cells via suppressing the JNK/caspase-3 pathway
por: Yuan, Yang, et al.
Publicado: (2023)

Neuroprotective Effects of Mitochondria-Targeted Plastoquinone in a Rat Model of Neonatal Hypoxic–Ischemic Brain Injury
por: Silachev, Denis N., et al.
Publicado: (2018)

Retraction: Isoflurane Preconditioning Confers Cardioprotection by Activation of ALDH2
Publicado: (2023)

Telomerase confers resistance to caspase-mediated apoptosis
por: Bermudez, Yira, et al.
Publicado: (2006)

Artemether confers neuroprotection on cerebral ischemic injury through stimulation of the Erk1/2-P90rsk-CREB signaling pathway
por: Li, Shuai, et al.
Publicado: (2021)

Non-invasive remote limb ischemic postconditioning protects rats against focal cerebral ischemia by upregulating STAT3 and reducing apoptosis
por: CHENG, ZHIGANG, et al.
Publicado: (2014)

Combination of Therapeutic Hypothermia and Other Neuroprotective Strategies after An Ischemic Cerebral Insult#
por: Goossens, Joline, et al.
Publicado: (2014)

Paradigms and mechanisms of inhalational anesthetics mediated neuroprotection against cerebral ischemic stroke
por: Wang, Hailian, et al.
Publicado: (2016)

Neuroprotective effects of TRPA1 channels in the cerebral endothelium following ischemic stroke
por: Pires, Paulo Wagner, et al.
Publicado: (2018)

Overview of Experimental and Clinical Findings regarding the Neuroprotective Effects of Cerebral Ischemic Postconditioning
por: Ma, Di, et al.
Publicado: (2017)

The neuroprotective mechanisms of ginkgolides and bilobalide in cerebral ischemic injury: a literature review
por: Feng, Zili, et al.
Publicado: (2019)

Ocular neuroprotection by siRNA targeting caspase-2
por: Ahmed, Z, et al.
Publicado: (2011)

Staphylococcus haemolyticus strains target mitochondria and induce caspase-dependent apoptosis of macrophages
por: Krzymińska, Sylwia, et al.
Publicado: (2012)

Caspase-2 resides in the mitochondria and mediates apoptosis directly from the mitochondrial compartment
por: Lopez-Cruzan, M, et al.
Publicado: (2016)

Involvement of JNK and Caspase Activation in Hoiamide A-Induced Neurotoxicity in Neocortical Neurons
por: Cao, Zhengyu, et al.
Publicado: (2015)

Ischemic Stroke and Neuroprotection
por: Onwuekwe, IO, et al.
Publicado: (2012)

UBIAD1 alleviates ferroptotic neuronal death by enhancing antioxidative capacity by cooperatively restoring impaired mitochondria and Golgi apparatus upon cerebral ischemic/reperfusion insult
por: Huang, Yan, et al.
Publicado: (2022)

Berberine confers neuroprotection in coping with focal cerebral ischemia by targeting inflammatory cytokines
por: Maleki, Solmaz Nasseri, et al.
Publicado: (2018)

Pinocembrin alleviates memory impairment in transient global cerebral ischemic rats
por: MENG, FANRUI, et al.
Publicado: (2014)

Ischemia preconditioning is neuroprotective in a rat cerebral ischemic injury model through autophagy activation and apoptosis inhibition
por: Xia, D.Y., et al.
Publicado: (2013)

TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotection upon Ischemic Stroke in Mice
por: Zeng, Jianxiong, et al.
Publicado: (2023)

Inhibition of insulin-regulated aminopeptidase confers neuroprotection in a conscious model of ischemic stroke
por: Telianidis, Jonathon, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_q2ctiersfpjaqli1qjkac6e18m