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A Primary Role for α-Cells as Amino Acid Sensors
Glucagon and its partner insulin are dually linked in both their secretion from islet cells and their action in the liver. Glucagon signaling increases hepatic glucose output, and hyperglucagonemia is partly responsible for the hyperglycemia in diabetes, making glucagon an attractive target for ther...
Autor principal: | Dean, E. Danielle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085241/ https://www.ncbi.nlm.nih.gov/pubmed/31653720 http://dx.doi.org/10.2337/dbi19-0021 |
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