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Cerebrospinal fluid neurofilament light concentration predicts brain atrophy and cognition in Alzheimer's disease

INTRODUCTION: This study assessed the utility of cerebrospinal fluid (CSF) neurofilament light (NfL) in Alzheimer's disease (AD) diagnosis, its association with amyloid and tau pathology, as well as its potential to predict brain atrophy, cognition, and amyloid accumulation. METHODS: CSF NfL co...

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Detalles Bibliográficos
Autores principales: Dhiman, Kunal, Gupta, Veer Bala, Villemagne, Victor L., Eratne, Dhamidhu, Graham, Petra L., Fowler, Christopher, Bourgeat, Pierrick, Li, Qiao‐Xin, Collins, Steven, Bush, Ashley I., Rowe, Christopher C., Masters, Colin L., Ames, David, Hone, Eugene, Blennow, Kaj, Zetterberg, Henrik, Martins, Ralph N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085283/
https://www.ncbi.nlm.nih.gov/pubmed/32211500
http://dx.doi.org/10.1002/dad2.12005