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Genetic and regulatory architecture of Alzheimer's disease in the APOE region

INTRODUCTION: Apolipoprotein E (APOE) ε2 and ε4 alleles encoded by rs7412 and rs429358 polymorphisms, respectively, are landmark contra and pro “risk” factors for Alzheimer's disease (AD). METHODS: We examined differences in linkage disequilibrium (LD) structures between (1) AD‐affected and una...

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Detalles Bibliográficos
Autores principales:	Kulminski, Alexander M., Shu, Leonardo, Loika, Yury, He, Liang, Nazarian, Alireza, Arbeev, Konstantin, Ukraintseva, Svetlana, Yashin, Anatoliy, Culminskaya, Irina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085286/ https://www.ncbi.nlm.nih.gov/pubmed/32211503 http://dx.doi.org/10.1002/dad2.12008

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