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Deep Transfer Learning Models for Medical Diabetic Retinopathy Detection

INTRODUCTION: Diabetic retinopathy (DR) is the most common diabetic eye disease worldwide and a leading cause of blindness. The number of diabetic patients will increase to 552 million by 2034, as per the International Diabetes Federation (IDF). AIM: With advances in computer science techniques, suc...

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Autores principales: Khalifa, Nour Eldeen M., Loey, Mohamed, Taha, Mohamed Hamed N., Mohamed, Hamed Nasr Eldin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academy of Medical sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085308/
https://www.ncbi.nlm.nih.gov/pubmed/32210500
http://dx.doi.org/10.5455/aim.2019.27.327-332
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author Khalifa, Nour Eldeen M.
Loey, Mohamed
Taha, Mohamed Hamed N.
Mohamed, Hamed Nasr Eldin T.
author_facet Khalifa, Nour Eldeen M.
Loey, Mohamed
Taha, Mohamed Hamed N.
Mohamed, Hamed Nasr Eldin T.
author_sort Khalifa, Nour Eldeen M.
collection PubMed
description INTRODUCTION: Diabetic retinopathy (DR) is the most common diabetic eye disease worldwide and a leading cause of blindness. The number of diabetic patients will increase to 552 million by 2034, as per the International Diabetes Federation (IDF). AIM: With advances in computer science techniques, such as artificial intelligence (AI) and deep learning (DL), opportunities for the detection of DR at the early stages have increased. This increase means that the chances of recovery will increase and the possibility of vision loss in patients will be reduced in the future. METHODS: In this paper, deep transfer learning models for medical DR detection were investigated. The DL models were trained and tested over the Asia Pacific Tele-Ophthalmology Society (APTOS) 2019 dataset. According to literature surveys, this research is considered one the first studies to use of the APTOS 2019 dataset, as it was freshly published in the second quarter of 2019. The selected deep transfer models in this research were AlexNet, Res-Net18, SqueezeNet, GoogleNet, VGG16, and VGG19. These models were selected, as they consist of a small number of layers when compared to larger models, such as DenseNet and InceptionResNet. Data augmentation techniques were used to render the models more robust and to overcome the overfitting problem. RESULTS: The testing accuracy and performance metrics, such as the precision, recall, and F1 score, were calculated to prove the robustness of the selected models. The AlexNet model achieved the highest testing accuracy at 97.9%. In addition, the achieved performance metrics strengthened our achieved results. Moreover, AlexNet has a minimum number of layers, which decreases the training time and the computational complexity.
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spelling pubmed-70853082020-03-24 Deep Transfer Learning Models for Medical Diabetic Retinopathy Detection Khalifa, Nour Eldeen M. Loey, Mohamed Taha, Mohamed Hamed N. Mohamed, Hamed Nasr Eldin T. Acta Inform Med Original Paper INTRODUCTION: Diabetic retinopathy (DR) is the most common diabetic eye disease worldwide and a leading cause of blindness. The number of diabetic patients will increase to 552 million by 2034, as per the International Diabetes Federation (IDF). AIM: With advances in computer science techniques, such as artificial intelligence (AI) and deep learning (DL), opportunities for the detection of DR at the early stages have increased. This increase means that the chances of recovery will increase and the possibility of vision loss in patients will be reduced in the future. METHODS: In this paper, deep transfer learning models for medical DR detection were investigated. The DL models were trained and tested over the Asia Pacific Tele-Ophthalmology Society (APTOS) 2019 dataset. According to literature surveys, this research is considered one the first studies to use of the APTOS 2019 dataset, as it was freshly published in the second quarter of 2019. The selected deep transfer models in this research were AlexNet, Res-Net18, SqueezeNet, GoogleNet, VGG16, and VGG19. These models were selected, as they consist of a small number of layers when compared to larger models, such as DenseNet and InceptionResNet. Data augmentation techniques were used to render the models more robust and to overcome the overfitting problem. RESULTS: The testing accuracy and performance metrics, such as the precision, recall, and F1 score, were calculated to prove the robustness of the selected models. The AlexNet model achieved the highest testing accuracy at 97.9%. In addition, the achieved performance metrics strengthened our achieved results. Moreover, AlexNet has a minimum number of layers, which decreases the training time and the computational complexity. Academy of Medical sciences 2019-12 /pmc/articles/PMC7085308/ /pubmed/32210500 http://dx.doi.org/10.5455/aim.2019.27.327-332 Text en © 2019 Nour Eldeen M. Khalifa, Mohamed Loey, Mohamed Hamed N. Taha, Hamed Nasr Eldin T. Mohamed http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Paper
Khalifa, Nour Eldeen M.
Loey, Mohamed
Taha, Mohamed Hamed N.
Mohamed, Hamed Nasr Eldin T.
Deep Transfer Learning Models for Medical Diabetic Retinopathy Detection
title Deep Transfer Learning Models for Medical Diabetic Retinopathy Detection
title_full Deep Transfer Learning Models for Medical Diabetic Retinopathy Detection
title_fullStr Deep Transfer Learning Models for Medical Diabetic Retinopathy Detection
title_full_unstemmed Deep Transfer Learning Models for Medical Diabetic Retinopathy Detection
title_short Deep Transfer Learning Models for Medical Diabetic Retinopathy Detection
title_sort deep transfer learning models for medical diabetic retinopathy detection
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085308/
https://www.ncbi.nlm.nih.gov/pubmed/32210500
http://dx.doi.org/10.5455/aim.2019.27.327-332
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