Cargando…
Dual SGLT1/SGLT2 Inhibitor Phlorizin Ameliorates Non-Alcoholic Fatty Liver Disease and Hepatic Glucose Production in Type 2 Diabetic Mice
PURPOSE: NAFLD is a hepatic component of type 2 diabetes mellitus (T2D), in which impaired hepatic glucose production plays an important role. Inhibitors of sodium glucose transporter 2 (SGLT2) reduce glycemia and exert beneficial effects on diabetic complications. Recently, dual SGLT1/2 inhibition...
Autores principales: | David-Silva, Aline, Esteves, João Victor, Morais, Mychel Raony P T, Freitas, Helayne Soares, Zorn, Telma Maria, Correa-Giannella, Maria Lucia, Machado, Ubiratan Fabres |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085338/ https://www.ncbi.nlm.nih.gov/pubmed/32231437 http://dx.doi.org/10.2147/DMSO.S242282 |
Ejemplares similares
-
Increased SGLT1 expression in salivary gland ductal cells correlates with hyposalivation in diabetic and hypertensive rats
por: Sabino-Silva, Robinson, et al.
Publicado: (2013) -
Resveratrol improves glycemic control in insulin-treated diabetic rats: participation of the hepatic territory
por: Yonamine, Caio Yogi, et al.
Publicado: (2016) -
Contribution of hyperglycemia on diabetic complications in obese type 2
diabetic SDT fatty rats: effects of SGLT inhibitor phlorizin
por: KATSUDA, Yoshiaki, et al.
Publicado: (2015) -
Sotagliflozin, a dual SGLT1 and SGLT2 inhibitor: In the heart of the problem
por: Vallianou, Natalia G., et al.
Publicado: (2021) -
Expression of SGLT1 in Human Hearts and Impairment of Cardiac Glucose Uptake by Phlorizin during Ischemia-Reperfusion Injury in Mice
por: Kashiwagi, Yusuke, et al.
Publicado: (2015)