Dosimetric Comparison of Three Radiotherapy Techniques in Irradiation of Left-Sided Breast Cancer Patients after Radical Mastectomy

RESULTS: The VMAT plans showed superior to PTV dose conformity index (CI), homogeneity index (HI), protection of the ipsilateral lung, monitor units (MUs), and maximum dose (D(max)) to the contralateral breast compared with TSP and 9FIMRT plans. The TSP provided better protection for D(mean) of the heart and left ventricle (p < 0.05). A dose for left anterior descending artery from the three techniques had no significant difference. Compared with the 9FIMRT plans, the V(5Gy) (%) and V(10Gy) (%) for the ipsilateral lung were significantly reduced with TSP and VMAT (p < 0.05). The V(5Gy) (%) and V(10Gy) (%) for the ipsilateral lung turned out to be similar between VMAT and TSP techniques. CONCLUSIONS: Our study indicates that VMAT should be a better choice of radiotherapy for left-sided breast cancer patients after radical mastectomy. If VMAT is unavailable, 9FIMRT can achieve better CI and HI values and be more MU-efficient compared with TSP; however, TSP can effectively reduce the low dose volume of the ipsilateral lungs and heart.