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Finite Element Analysis of Interface Dependence on Nanomechanical Sensing

Nanomechanical sensors and their arrays have been attracting significant attention for detecting, discriminating and identifying target analytes. The sensing responses can be partially explained by the physical properties of the receptor layers coated on the sensing elements. Analytical solutions of...

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Autores principales: Minami, Kosuke, Yoshikawa, Genki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085745/
https://www.ncbi.nlm.nih.gov/pubmed/32164172
http://dx.doi.org/10.3390/s20051518
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author Minami, Kosuke
Yoshikawa, Genki
author_facet Minami, Kosuke
Yoshikawa, Genki
author_sort Minami, Kosuke
collection PubMed
description Nanomechanical sensors and their arrays have been attracting significant attention for detecting, discriminating and identifying target analytes. The sensing responses can be partially explained by the physical properties of the receptor layers coated on the sensing elements. Analytical solutions of nanomechanical sensing are available for a simple cantilever model including the physical parameters of both a cantilever and a receptor layer. These analytical solutions generally rely on the simple structures, such that the sensing element and the receptor layer are fully attached at their boundary. However, an actual interface in a real system is not always fully attached because of inhomogeneous coatings with low affinity to the sensor surface or partial detachments caused by the exposure to some analytes, especially with high concentration. Here, we study the effects of such macroscopic interfacial structures, including partial attachments/detachments, for static nanomechanical sensing, focusing on a Membrane-type Surface stress Sensor (MSS), through finite element analysis (FEA). We simulate various macroscopic interfacial structures by changing the sizes, numbers and positions of the attachments as well as the elastic properties of receptor layers (e.g., Young’s modulus and Poisson’s ratio) and evaluate the effects on the sensitivity. It is found that specific interfacial structures lead to efficient sensing responses, providing a guideline for designing the coating films as well as optimizing the interfacial structures for higher sensitivity including surface modification of the substrate.
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spelling pubmed-70857452020-03-25 Finite Element Analysis of Interface Dependence on Nanomechanical Sensing Minami, Kosuke Yoshikawa, Genki Sensors (Basel) Article Nanomechanical sensors and their arrays have been attracting significant attention for detecting, discriminating and identifying target analytes. The sensing responses can be partially explained by the physical properties of the receptor layers coated on the sensing elements. Analytical solutions of nanomechanical sensing are available for a simple cantilever model including the physical parameters of both a cantilever and a receptor layer. These analytical solutions generally rely on the simple structures, such that the sensing element and the receptor layer are fully attached at their boundary. However, an actual interface in a real system is not always fully attached because of inhomogeneous coatings with low affinity to the sensor surface or partial detachments caused by the exposure to some analytes, especially with high concentration. Here, we study the effects of such macroscopic interfacial structures, including partial attachments/detachments, for static nanomechanical sensing, focusing on a Membrane-type Surface stress Sensor (MSS), through finite element analysis (FEA). We simulate various macroscopic interfacial structures by changing the sizes, numbers and positions of the attachments as well as the elastic properties of receptor layers (e.g., Young’s modulus and Poisson’s ratio) and evaluate the effects on the sensitivity. It is found that specific interfacial structures lead to efficient sensing responses, providing a guideline for designing the coating films as well as optimizing the interfacial structures for higher sensitivity including surface modification of the substrate. MDPI 2020-03-10 /pmc/articles/PMC7085745/ /pubmed/32164172 http://dx.doi.org/10.3390/s20051518 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Minami, Kosuke
Yoshikawa, Genki
Finite Element Analysis of Interface Dependence on Nanomechanical Sensing
title Finite Element Analysis of Interface Dependence on Nanomechanical Sensing
title_full Finite Element Analysis of Interface Dependence on Nanomechanical Sensing
title_fullStr Finite Element Analysis of Interface Dependence on Nanomechanical Sensing
title_full_unstemmed Finite Element Analysis of Interface Dependence on Nanomechanical Sensing
title_short Finite Element Analysis of Interface Dependence on Nanomechanical Sensing
title_sort finite element analysis of interface dependence on nanomechanical sensing
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085745/
https://www.ncbi.nlm.nih.gov/pubmed/32164172
http://dx.doi.org/10.3390/s20051518
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