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Accurate annotation of human protein-coding small open reading frames

Functional protein-coding small open reading frames (smORFs) are emerging as an important class of genes. However, the number of translated smORFs in the human genome is unclear because proteogenomic methods are not sensitive enough, and, as we show, Ribo-Seq strategies require additional measures t...

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Detalles Bibliográficos
Autores principales: Martinez, Thomas F., Chu, Qian, Donaldson, Cynthia, Tan, Dan, Shokhirev, Maxim N., Saghatelian, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085969/
https://www.ncbi.nlm.nih.gov/pubmed/31819274
http://dx.doi.org/10.1038/s41589-019-0425-0