Radiprodil, a NR2B negative allosteric modulator, from bench to bedside in infantile spasm syndrome

OBJECTIVE: Infantile spasm syndrome (ISS) is an epileptic encephalopathy without established treatment after the failure to standard of care based on steroids and vigabatrin. Converging lines of evidence indicating a role of NR2B subunits of the N‐methyl‐D‐aspartate (NMDA) receptor on the onset of s...

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Detalles Bibliográficos
Autores principales: Auvin, Stéphane, Dozières‐Puyravel, Blandine, Avbersek, Andreja, Sciberras, David, Collier, Jo, Leclercq, Karine, Mares, Pavel, Kaminski, Rafal M., Muglia, Pierandrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085998/
https://www.ncbi.nlm.nih.gov/pubmed/32106360
http://dx.doi.org/10.1002/acn3.50998

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