Cardiac FGF23: a new player in myocardial infarction

Fibroblast Growth Factor 23 (FGF23) is a hormone involved in phosphate metabolism. It is known that FGF23 is increased in different pathologies including chronic kidney disease, heart failure or X-linked hypophosphatemia and directly correlates with negative outcome and mortality in severe diseases....

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Detalles Bibliográficos
Autores principales: Schumacher, David, Schuh, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Applied Systems srl 2019
Materias:
Focused Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086082/
https://www.ncbi.nlm.nih.gov/pubmed/32309615
http://dx.doi.org/10.15190/d.2019.10
Descripción
Sumario:Fibroblast Growth Factor 23 (FGF23) is a hormone involved in phosphate metabolism. It is known that FGF23 is increased in different pathologies including chronic kidney disease, heart failure or X-linked hypophosphatemia and directly correlates with negative outcome and mortality in severe diseases. However, the role of FGF23 in cardiovascular pathologies is still under debate. This review summarizes the current knowledge about the role of FGF23 in ischemic heart diseases, such as myocardial infarction.

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