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Isolated Area Postrema Syndrome Presenting as Intractable Nausea and Vomiting
Neuromyelitis optica (NMO) is a disease of central nervous system, characterized by demyelination and axonal damage mostly involving optic nerves and spinal cord. Usually these patients present with symptoms related to optic neuritis or myelitis with a typical relapsing course. Some patients present...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086113/ https://www.ncbi.nlm.nih.gov/pubmed/32219052 http://dx.doi.org/10.7759/cureus.7058 |
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author | Dandu, Vasuki Siddamreddy, Suman Meegada, Sreenath Muppidi, Vijayadershan Challa, Tejo |
author_facet | Dandu, Vasuki Siddamreddy, Suman Meegada, Sreenath Muppidi, Vijayadershan Challa, Tejo |
author_sort | Dandu, Vasuki |
collection | PubMed |
description | Neuromyelitis optica (NMO) is a disease of central nervous system, characterized by demyelination and axonal damage mostly involving optic nerves and spinal cord. Usually these patients present with symptoms related to optic neuritis or myelitis with a typical relapsing course. Some patients present with less common symptoms involving brain stem like nausea and vomiting, especially those involving area postrema (AP) located in dorsal medulla. International panel for NMO diagnosis revised criteria in 2015 and came up with a unifying term NMO spectrum disorders (NMOSD) instead of NMO. Patients with NMO having AP involvement are grouped under area postrema syndrome (APS). Usually patients with AP symptoms also have neurological symptoms upon presentation. Here we present a rare case of an NMO who presented with isolated APS with no other neurological symptoms. |
format | Online Article Text |
id | pubmed-7086113 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-70861132020-03-26 Isolated Area Postrema Syndrome Presenting as Intractable Nausea and Vomiting Dandu, Vasuki Siddamreddy, Suman Meegada, Sreenath Muppidi, Vijayadershan Challa, Tejo Cureus Internal Medicine Neuromyelitis optica (NMO) is a disease of central nervous system, characterized by demyelination and axonal damage mostly involving optic nerves and spinal cord. Usually these patients present with symptoms related to optic neuritis or myelitis with a typical relapsing course. Some patients present with less common symptoms involving brain stem like nausea and vomiting, especially those involving area postrema (AP) located in dorsal medulla. International panel for NMO diagnosis revised criteria in 2015 and came up with a unifying term NMO spectrum disorders (NMOSD) instead of NMO. Patients with NMO having AP involvement are grouped under area postrema syndrome (APS). Usually patients with AP symptoms also have neurological symptoms upon presentation. Here we present a rare case of an NMO who presented with isolated APS with no other neurological symptoms. Cureus 2020-02-20 /pmc/articles/PMC7086113/ /pubmed/32219052 http://dx.doi.org/10.7759/cureus.7058 Text en Copyright © 2020, Dandu et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Dandu, Vasuki Siddamreddy, Suman Meegada, Sreenath Muppidi, Vijayadershan Challa, Tejo Isolated Area Postrema Syndrome Presenting as Intractable Nausea and Vomiting |
title | Isolated Area Postrema Syndrome Presenting as Intractable Nausea and Vomiting |
title_full | Isolated Area Postrema Syndrome Presenting as Intractable Nausea and Vomiting |
title_fullStr | Isolated Area Postrema Syndrome Presenting as Intractable Nausea and Vomiting |
title_full_unstemmed | Isolated Area Postrema Syndrome Presenting as Intractable Nausea and Vomiting |
title_short | Isolated Area Postrema Syndrome Presenting as Intractable Nausea and Vomiting |
title_sort | isolated area postrema syndrome presenting as intractable nausea and vomiting |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086113/ https://www.ncbi.nlm.nih.gov/pubmed/32219052 http://dx.doi.org/10.7759/cureus.7058 |
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