Blockade of the mTOR signaling pathway with rapamycin ameliorates aristolochic acid nephropathy

Chronic aristolochic acid nephropathy (CAAN) is characterized by widespread apoptosis and interstitial fibrosis, which severely impairs kidney function. mTOR is crucial for cell proliferation and protein synthesis. In the present study, the therapeutic effects of blockade of mTOR activity by rapamyc...

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Detalles Bibliográficos
Autores principales: Wu, Minmin, Tang, Lili, Chen, Bicheng, Zheng, Jianjian, Dong, Fengquan, Su, Zhen, Lin, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086201/
https://www.ncbi.nlm.nih.gov/pubmed/32256773
http://dx.doi.org/10.3892/etm.2020.8550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086201/
https://www.ncbi.nlm.nih.gov/pubmed/32256773
http://dx.doi.org/10.3892/etm.2020.8550

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