Cargando…

Hydroxysafflor yellow A induces autophagy in human liver cancer cells by regulating Beclin 1 and ERK expression

Hydroxysafflor yellow A (HSYA) is a water-soluble component of the safflower (Carthamus tinctorius), and research has revealed that HSYA exhibits antitumor effects. In the present study, the effects of HSYA on the autophagy of a Hep-G2 liver cancer cell line, as well as the underlying mechanisms, we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Ziwei, Liu, Li, Liu, Yueyun, Wang, Shuyan, Zhang, Shujing, Dong, Ruijuan, Xu, Mingyang, Ma, Yicong, Wang, Jingjing, Zhang, Qian, Wei, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086224/ https://www.ncbi.nlm.nih.gov/pubmed/32256785 http://dx.doi.org/10.3892/etm.2020.8552

Ejemplares similares

Establishment of Fluorescence Sensitization Method for Hydroxysafflor Yellow A
por: Haiyan, CAO, et al.
Publicado: (2020)

Mechanism of hydroxysafflor yellow A on acute liver injury based on transcriptomics
por: Hou, Xiangmei, et al.
Publicado: (2022)

Hydroxysafflor-Yellow A Induces Human Gastric Carcinoma BGC-823 Cell Apoptosis by Activating Peroxisome Proliferator-Activated Receptor Gamma (PPARγ)
por: Liu, Li, et al.
Publicado: (2018)

Superior Stability of Hydroxysafflor Yellow A in Xuebijing Injection and the Associated Mechanism
por: Pu, Weiling, et al.
Publicado: (2017)

Nanoemulsions of Hydroxysafflor Yellow A for Enhancing Physicochemical and In Vivo Performance
por: Zhang, Yingjie, et al.
Publicado: (2023)

Protective effect of hydroxysafflor yellow A on MSCs against senescence induced by d-galactose
por: Song, Xiaoqing, et al.
Publicado: (2022)

Hydroxysafflor yellow A improved retinopathy via Nrf2/HO-1 pathway in rats
por: Sun, Zhihui, et al.
Publicado: (2022)

Hydroxysafflor Yellow A Protects Against Myocardial Ischemia/Reperfusion Injury via Suppressing NLRP3 Inflammasome and Activating Autophagy
por: Ye, Jingxue, et al.
Publicado: (2020)

Therapeutic Potential of Hydroxysafflor Yellow A on Cardio-Cerebrovascular Diseases
por: Bai, Xue, et al.
Publicado: (2020)

Integrating Network Pharmacology and Transcriptomic Strategies to Explore the Pharmacological Mechanism of Hydroxysafflor Yellow A in Delaying Liver Aging
por: Kong, Jie, et al.
Publicado: (2022)

Hydroxysafflor Yellow A (HSYA) Protects Endplate Chondrocytes Against IL-1β-Induced Injury Through Promoting Autophagy
por: Zhang, Zongyu, et al.
Publicado: (2022)

Hydroxysafflor yellow A attenuates the expression of inflammatory cytokines in acute soft tissue injury
por: Dong, Fang, et al.
Publicado: (2017)

Hydroxysafflor yellow A protects against angiotensin II-induced hypertrophy
por: Ni, Bin, et al.
Publicado: (2018)

Rapamycin Inhibits Cardiac Hypertrophy by Promoting Autophagy via the MEK/ERK/Beclin-1 Pathway
por: Gu, Jun, et al.
Publicado: (2016)

Corrigendum: Hydroxysafflor Yellow A Protects Against Myocardial Ischemia/Reperfusion Injury via Suppressing NLRP3 Inflammasome and Activating Autophagy
por: Ye, Jingxue, et al.
Publicado: (2021)

Hydroxysafflor Yellow A protects spinal cords from ischemia/reperfusion injury in rabbits
por: Shan, Le-qun, et al.
Publicado: (2010)

Hydroxysafflor yellow A exerts antioxidant effects in a rat model of traumatic brain injury
por: Wang, Yang, et al.
Publicado: (2016)

Hydroxysafflor Yellow A Protects Neurons From Excitotoxic Death through Inhibition of NMDARs
por: Wang, Xingtao, et al.
Publicado: (2016)

Hydroxysafflor Yellow A Ameliorates Myocardial Ischemia/Reperfusion Injury by Suppressing Calcium Overload and Apoptosis
por: Ye, Jingxue, et al.
Publicado: (2021)

Hydroxysafflor Yellow A: A Promising Therapeutic Agent for a Broad Spectrum of Diseases
por: Ao, Hui, et al.
Publicado: (2018)

Hydroxysafflor yellow A improves established monocrotaline-induced pulmonary arterial hypertension in rats
por: Han, Xiaotong, et al.
Publicado: (2016)

Hydroxysafflor Yellow A Attenuates Lipopolysaccharide-Induced Neurotoxicity and Neuroinflammation in Primary Mesencephalic Cultures
por: Wang, Tian, et al.
Publicado: (2018)

Proteomic investigation of effects of hydroxysafflor yellow A in oxidized low-density lipoprotein-induced endothelial injury
por: Ye, Feng, et al.
Publicado: (2017)

Co-delivery of deferoxamine and hydroxysafflor yellow A to accelerate diabetic wound healing via enhanced angiogenesis
por: Gao, Si-Qian, et al.
Publicado: (2018)

Protective potential of hydroxysafflor yellow A in cerebral ischemia and reperfusion injury: An overview of evidence from experimental studies
por: Yu, Lu, et al.
Publicado: (2022)

Synergistic neuroprotective effects of Danshensu and hydroxysafflor yellow A on cerebral ischemia-reperfusion injury in rats
por: Xu, Hang, et al.
Publicado: (2017)

Hydroxysafflor Yellow A Exerts Neuroprotective Effects via HIF-1α/BNIP3 Pathway to Activate Neuronal Autophagy after OGD/R
por: Wei, Ruheng, et al.
Publicado: (2022)

Paeoniflorin and Hydroxysafflor Yellow A in Xuebijing Injection Attenuate Sepsis-Induced Cardiac Dysfunction and Inhibit Proinflammatory Cytokine Production
por: Wang, Xin-Tong, et al.
Publicado: (2021)

Enhanced effect and mechanism of water-in-oil microemulsion as an oral delivery system of hydroxysafflor yellow A
por: Qi, Jianping, et al.
Publicado: (2011)

Hydroxysafflor Yellow A Ameliorates Renal Fibrosis by Suppressing TGF-β1-Induced Epithelial-to-Mesenchymal Transition
por: Hu, Naping, et al.
Publicado: (2016)

Hydroxysafflor Yellow A Promoted Bone Mineralization and Inhibited Bone Resorption Which Reversed Glucocorticoids-Induced Osteoporosis
por: Liu, Li, et al.
Publicado: (2018)

Hydroxysafflor Yellow A Shows Protection against PPARγ Inactivation in Nitrosative Neurons
por: Sun, Li, et al.
Publicado: (2018)

Inhibition of Beclin-1-Mediated Autophagy by MicroRNA-17-5p Enhanced the Radiosensitivity of Glioma Cells
por: Hou, Weichen, et al.
Publicado: (2017)

Hydroxysafflor Yellow A Blocks HIF-1α Induction of NOX2 and Protects ZO-1 Protein in Cerebral Microvascular Endothelium
por: Li, Yi, et al.
Publicado: (2022)

Metabolomics reveals the effects of hydroxysafflor yellow A on neurogenesis and axon regeneration after experimental traumatic brain injury
por: Hu, En, et al.
Publicado: (2023)

Protective effect of hydroxysafflor yellow A on cyclosporin A-induced renal oxidative stress in vitro and in vivo
por: Wang, Jiyuan, et al.
Publicado: (2022)

Pharmacological Actions, Molecular Mechanisms, Pharmacokinetic Progressions, and Clinical Applications of Hydroxysafflor Yellow A in Antidiabetic Research
por: Zhang, Xilan, et al.
Publicado: (2021)

Hydroxysafflor Yellow A Exerts Anti-Inflammatory Effects Mediated by SIRT1 in Lipopolysaccharide-Induced Microglia Activation
por: Qin, Xiude, et al.
Publicado: (2020)

Hydroxysafflor Yellow A Phytosomes Administered via Intervaginal Space Injection Ameliorate Pulmonary Fibrosis in Mice
por: Li, Tingting, et al.
Publicado: (2022)

Restorative effects of hydroxysafflor yellow A on hepatic function in an experimental regression model of hepatic fibrosis induced by carbon tetrachloride
por: Li, Yanuo, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_4iop5pci919vofp3q24aeqk2u3