Markedly Effective Steroid Treatment of Three Patients with Allergy-related Jackhammer Esophagus

We experienced marked efficacy with steroid treatment of three patients with jackhammer esophagus (JHE). An esophageal biopsy revealed eosinophilic esophagitis (EoE) in two patients. One of the patients without EoE had eosinophilia and an increased serum immunoglobulin E level, and endoscopic ultras...

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Detalles Bibliográficos
Autores principales: Funaki, Yasushi, Ogasawara, Naotaka, Kawamura, Yurika, Yoshimine, Takashi, Tamura, Yasuhiro, Izawa, Shinya, Tsuyuki, Takuji, Ebi, Masahide, Sasaki, Makoto, Kasugai, Kunio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086336/
https://www.ncbi.nlm.nih.gov/pubmed/31708550
http://dx.doi.org/10.2169/internalmedicine.3865-19
Descripción
Sumario:We experienced marked efficacy with steroid treatment of three patients with jackhammer esophagus (JHE). An esophageal biopsy revealed eosinophilic esophagitis (EoE) in two patients. One of the patients without EoE had eosinophilia and an increased serum immunoglobulin E level, and endoscopic ultrasonography revealed thickening of the esophageal muscularis propria. Esophageal manometry was used to diagnose all cases of JHE. Treatment consisted of steroid administration, which improved the symptoms and resolved the esophageal muscularis propria thickening in all patients. The esophageal manometry findings also normalized following treatment. Allergic diseases, including EoE, were assumed to have caused JHE.

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