F-box proteins and cancer: an update from functional and regulatory mechanism to therapeutic clinical prospects

E3 ubiquitin ligases play a critical role in cellular mechanisms and cancer progression. F-box protein is the core component of the SKP1-cullin 1-F-box (SCF)-type E3 ubiquitin ligase and directly binds to substrates by various specific domains. According to the specific domains, F-box proteins are f...

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Detalles Bibliográficos
Autores principales: Tekcham, Dinesh Singh, Chen, Di, Liu, Yu, Ling, Ting, Zhang, Yi, Chen, Huan, Wang, Wen, Otkur, Wuxiyar, Qi, Huan, Xia, Tian, Liu, Xiaolong, Piao, Hai-long, Liu, Hongxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086354/
https://www.ncbi.nlm.nih.gov/pubmed/32226545
http://dx.doi.org/10.7150/thno.42735

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