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Nuclear receptor ERRα contributes to castration-resistant growth of prostate cancer via its regulation of intratumoral androgen biosynthesis

Enhanced intratumoral androgen biosynthesis and persistent androgen receptor (AR) signaling are key factors responsible for the relapse growth of castration-resistant prostate cancer (CRPC). Residual intraprostatic androgens can be produced by de novo synthesis of androgens from cholesterol or conve...

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Detalles Bibliográficos
Autores principales:	Xu, Zhenyu, Ma, Taiyang, Zhou, Jianfu, Gao, Weijie, Li, Youjia, Yu, Shan, Wang, Yuliang, Chan, Franky Leung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086365/ https://www.ncbi.nlm.nih.gov/pubmed/32226548 http://dx.doi.org/10.7150/thno.35589

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