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Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review

Pharyngeal liposarcomas are very rare; still more rare are dedifferentiated liposarcomas in the pharynx. An 82-year-old man presented with dysphagia, voice changes, weight loss, nasal regurgitation of liquids, and coughing spells. A 3.5 cm mass was identified in the hypopharynx. The mass was biopsie...

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Detalles Bibliográficos
Autores principales: Wanes, Peter, Nolte, David A., Tranesh, Ghassan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086435/
https://www.ncbi.nlm.nih.gov/pubmed/32231834
http://dx.doi.org/10.1155/2020/2968467
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author Wanes, Peter
Nolte, David A.
Tranesh, Ghassan A.
author_facet Wanes, Peter
Nolte, David A.
Tranesh, Ghassan A.
author_sort Wanes, Peter
collection PubMed
description Pharyngeal liposarcomas are very rare; still more rare are dedifferentiated liposarcomas in the pharynx. An 82-year-old man presented with dysphagia, voice changes, weight loss, nasal regurgitation of liquids, and coughing spells. A 3.5 cm mass was identified in the hypopharynx. The mass was biopsied and diagnosed as a benign fibroepithelial polyp. Continued symptoms and airway obstruction prompted a pharyngectomy, and the mass was then diagnosed as dedifferentiated liposarcoma. Due to infrequency and subtle histological findings, liposarcomas of the head and neck can be misdiagnosed and recur.
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spelling pubmed-70864352020-03-30 Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review Wanes, Peter Nolte, David A. Tranesh, Ghassan A. Case Rep Pathol Case Report Pharyngeal liposarcomas are very rare; still more rare are dedifferentiated liposarcomas in the pharynx. An 82-year-old man presented with dysphagia, voice changes, weight loss, nasal regurgitation of liquids, and coughing spells. A 3.5 cm mass was identified in the hypopharynx. The mass was biopsied and diagnosed as a benign fibroepithelial polyp. Continued symptoms and airway obstruction prompted a pharyngectomy, and the mass was then diagnosed as dedifferentiated liposarcoma. Due to infrequency and subtle histological findings, liposarcomas of the head and neck can be misdiagnosed and recur. Hindawi 2020-03-11 /pmc/articles/PMC7086435/ /pubmed/32231834 http://dx.doi.org/10.1155/2020/2968467 Text en Copyright © 2020 Peter Wanes et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Wanes, Peter
Nolte, David A.
Tranesh, Ghassan A.
Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review
title Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review
title_full Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review
title_fullStr Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review
title_full_unstemmed Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review
title_short Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review
title_sort hypopharyngeal dedifferentiated liposarcoma in the mdm2 era: a case report and short review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086435/
https://www.ncbi.nlm.nih.gov/pubmed/32231834
http://dx.doi.org/10.1155/2020/2968467
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