Cargando…
Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review
Pharyngeal liposarcomas are very rare; still more rare are dedifferentiated liposarcomas in the pharynx. An 82-year-old man presented with dysphagia, voice changes, weight loss, nasal regurgitation of liquids, and coughing spells. A 3.5 cm mass was identified in the hypopharynx. The mass was biopsie...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086435/ https://www.ncbi.nlm.nih.gov/pubmed/32231834 http://dx.doi.org/10.1155/2020/2968467 |
_version_ | 1783509123250257920 |
---|---|
author | Wanes, Peter Nolte, David A. Tranesh, Ghassan A. |
author_facet | Wanes, Peter Nolte, David A. Tranesh, Ghassan A. |
author_sort | Wanes, Peter |
collection | PubMed |
description | Pharyngeal liposarcomas are very rare; still more rare are dedifferentiated liposarcomas in the pharynx. An 82-year-old man presented with dysphagia, voice changes, weight loss, nasal regurgitation of liquids, and coughing spells. A 3.5 cm mass was identified in the hypopharynx. The mass was biopsied and diagnosed as a benign fibroepithelial polyp. Continued symptoms and airway obstruction prompted a pharyngectomy, and the mass was then diagnosed as dedifferentiated liposarcoma. Due to infrequency and subtle histological findings, liposarcomas of the head and neck can be misdiagnosed and recur. |
format | Online Article Text |
id | pubmed-7086435 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-70864352020-03-30 Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review Wanes, Peter Nolte, David A. Tranesh, Ghassan A. Case Rep Pathol Case Report Pharyngeal liposarcomas are very rare; still more rare are dedifferentiated liposarcomas in the pharynx. An 82-year-old man presented with dysphagia, voice changes, weight loss, nasal regurgitation of liquids, and coughing spells. A 3.5 cm mass was identified in the hypopharynx. The mass was biopsied and diagnosed as a benign fibroepithelial polyp. Continued symptoms and airway obstruction prompted a pharyngectomy, and the mass was then diagnosed as dedifferentiated liposarcoma. Due to infrequency and subtle histological findings, liposarcomas of the head and neck can be misdiagnosed and recur. Hindawi 2020-03-11 /pmc/articles/PMC7086435/ /pubmed/32231834 http://dx.doi.org/10.1155/2020/2968467 Text en Copyright © 2020 Peter Wanes et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Wanes, Peter Nolte, David A. Tranesh, Ghassan A. Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review |
title | Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review |
title_full | Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review |
title_fullStr | Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review |
title_full_unstemmed | Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review |
title_short | Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review |
title_sort | hypopharyngeal dedifferentiated liposarcoma in the mdm2 era: a case report and short review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086435/ https://www.ncbi.nlm.nih.gov/pubmed/32231834 http://dx.doi.org/10.1155/2020/2968467 |
work_keys_str_mv | AT wanespeter hypopharyngealdedifferentiatedliposarcomainthemdm2eraacasereportandshortreview AT noltedavida hypopharyngealdedifferentiatedliposarcomainthemdm2eraacasereportandshortreview AT traneshghassana hypopharyngealdedifferentiatedliposarcomainthemdm2eraacasereportandshortreview |