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Pseudoviral hollow-cored vesicles in multiple sclerosis brain
Novel, superficially ‘virus-like’ hollow-cored particles 50–60 nm in diameter were found in the perivascular extracellular space of the brain from a patient who died with acute multiple sclerosis (MS). It is concluded that they are not virions but are derived from myelin undergoing vesicular demyeli...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer-Verlag
1979
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086663/ https://www.ncbi.nlm.nih.gov/pubmed/506692 http://dx.doi.org/10.1007/BF00691793 |
Sumario: | Novel, superficially ‘virus-like’ hollow-cored particles 50–60 nm in diameter were found in the perivascular extracellular space of the brain from a patient who died with acute multiple sclerosis (MS). It is concluded that they are not virions but are derived from myelin undergoing vesicular demyelination. This case demonstrates the need for caution in the interpretation of unusual electron microscopic appearances. |
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