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Pseudoviral hollow-cored vesicles in multiple sclerosis brain

Novel, superficially ‘virus-like’ hollow-cored particles 50–60 nm in diameter were found in the perivascular extracellular space of the brain from a patient who died with acute multiple sclerosis (MS). It is concluded that they are not virions but are derived from myelin undergoing vesicular demyeli...

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Detalles Bibliográficos
Autor principal: Kirk, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 1979
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086663/
https://www.ncbi.nlm.nih.gov/pubmed/506692
http://dx.doi.org/10.1007/BF00691793
Descripción
Sumario:Novel, superficially ‘virus-like’ hollow-cored particles 50–60 nm in diameter were found in the perivascular extracellular space of the brain from a patient who died with acute multiple sclerosis (MS). It is concluded that they are not virions but are derived from myelin undergoing vesicular demyelination. This case demonstrates the need for caution in the interpretation of unusual electron microscopic appearances.