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Pseudoviral hollow-cored vesicles in multiple sclerosis brain
Novel, superficially ‘virus-like’ hollow-cored particles 50–60 nm in diameter were found in the perivascular extracellular space of the brain from a patient who died with acute multiple sclerosis (MS). It is concluded that they are not virions but are derived from myelin undergoing vesicular demyeli...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer-Verlag
1979
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086663/ https://www.ncbi.nlm.nih.gov/pubmed/506692 http://dx.doi.org/10.1007/BF00691793 |
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author | Kirk, J. |
author_facet | Kirk, J. |
author_sort | Kirk, J. |
collection | PubMed |
description | Novel, superficially ‘virus-like’ hollow-cored particles 50–60 nm in diameter were found in the perivascular extracellular space of the brain from a patient who died with acute multiple sclerosis (MS). It is concluded that they are not virions but are derived from myelin undergoing vesicular demyelination. This case demonstrates the need for caution in the interpretation of unusual electron microscopic appearances. |
format | Online Article Text |
id | pubmed-7086663 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1979 |
publisher | Springer-Verlag |
record_format | MEDLINE/PubMed |
spelling | pubmed-70866632020-03-23 Pseudoviral hollow-cored vesicles in multiple sclerosis brain Kirk, J. Acta Neuropathol Short Original Communications Novel, superficially ‘virus-like’ hollow-cored particles 50–60 nm in diameter were found in the perivascular extracellular space of the brain from a patient who died with acute multiple sclerosis (MS). It is concluded that they are not virions but are derived from myelin undergoing vesicular demyelination. This case demonstrates the need for caution in the interpretation of unusual electron microscopic appearances. Springer-Verlag 1979 /pmc/articles/PMC7086663/ /pubmed/506692 http://dx.doi.org/10.1007/BF00691793 Text en © Springer-Verlag 1979 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Short Original Communications Kirk, J. Pseudoviral hollow-cored vesicles in multiple sclerosis brain |
title | Pseudoviral hollow-cored vesicles in multiple sclerosis brain |
title_full | Pseudoviral hollow-cored vesicles in multiple sclerosis brain |
title_fullStr | Pseudoviral hollow-cored vesicles in multiple sclerosis brain |
title_full_unstemmed | Pseudoviral hollow-cored vesicles in multiple sclerosis brain |
title_short | Pseudoviral hollow-cored vesicles in multiple sclerosis brain |
title_sort | pseudoviral hollow-cored vesicles in multiple sclerosis brain |
topic | Short Original Communications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086663/ https://www.ncbi.nlm.nih.gov/pubmed/506692 http://dx.doi.org/10.1007/BF00691793 |
work_keys_str_mv | AT kirkj pseudoviralhollowcoredvesiclesinmultiplesclerosisbrain |