Phylogenetic and recombination analysis of coronavirus HKU1, a novel coronavirus from patients with pneumonia

Phylogenetic trees constructed using predicted amino acid sequences of putative proteins of coronavirus HKU1 (CoV-HKU1) revealed that CoV-HKU1 formed a distinct branch among group 2 coronaviruses. Of the 14 trees from p65 to nsp10, nine showed that CoV-HKU1 was clustered with murine hepatitis virus....

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Detalles Bibliográficos
Autores principales: Woo, P. C. Y., Lau, S. K. P., Huang, Y., Tsoi, H.-W., Chan, K.-H., Yuen, K.-Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086700/
https://www.ncbi.nlm.nih.gov/pubmed/15986174
http://dx.doi.org/10.1007/s00705-005-0573-2
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author Woo, P. C. Y.
Lau, S. K. P.
Huang, Y.
Tsoi, H.-W.
Chan, K.-H.
Yuen, K.-Y.
author_facet Woo, P. C. Y.
Lau, S. K. P.
Huang, Y.
Tsoi, H.-W.
Chan, K.-H.
Yuen, K.-Y.
author_sort Woo, P. C. Y.
collection PubMed
description Phylogenetic trees constructed using predicted amino acid sequences of putative proteins of coronavirus HKU1 (CoV-HKU1) revealed that CoV-HKU1 formed a distinct branch among group 2 coronaviruses. Of the 14 trees from p65 to nsp10, nine showed that CoV-HKU1 was clustered with murine hepatitis virus. From nsp11, the topologies of the trees changed dramatically. For the eight trees from nsp11 to N, seven showed that the CoV-HKU1 branch was the first branch. The codon usage patterns of CoV-HKU1 differed significantly from those in other group 2 coronaviruses. Split decomposition analysis revealed that recombination events had occurred between CoV-HKU1 and other coronaviruses.
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spelling pubmed-70867002020-03-23 Phylogenetic and recombination analysis of coronavirus HKU1, a novel coronavirus from patients with pneumonia Woo, P. C. Y. Lau, S. K. P. Huang, Y. Tsoi, H.-W. Chan, K.-H. Yuen, K.-Y. Arch Virol Article Phylogenetic trees constructed using predicted amino acid sequences of putative proteins of coronavirus HKU1 (CoV-HKU1) revealed that CoV-HKU1 formed a distinct branch among group 2 coronaviruses. Of the 14 trees from p65 to nsp10, nine showed that CoV-HKU1 was clustered with murine hepatitis virus. From nsp11, the topologies of the trees changed dramatically. For the eight trees from nsp11 to N, seven showed that the CoV-HKU1 branch was the first branch. The codon usage patterns of CoV-HKU1 differed significantly from those in other group 2 coronaviruses. Split decomposition analysis revealed that recombination events had occurred between CoV-HKU1 and other coronaviruses. Springer-Verlag 2005-06-28 2005 /pmc/articles/PMC7086700/ /pubmed/15986174 http://dx.doi.org/10.1007/s00705-005-0573-2 Text en © Springer-Verlag/Wien 2005 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Woo, P. C. Y.
Lau, S. K. P.
Huang, Y.
Tsoi, H.-W.
Chan, K.-H.
Yuen, K.-Y.
Phylogenetic and recombination analysis of coronavirus HKU1, a novel coronavirus from patients with pneumonia
title Phylogenetic and recombination analysis of coronavirus HKU1, a novel coronavirus from patients with pneumonia
title_full Phylogenetic and recombination analysis of coronavirus HKU1, a novel coronavirus from patients with pneumonia
title_fullStr Phylogenetic and recombination analysis of coronavirus HKU1, a novel coronavirus from patients with pneumonia
title_full_unstemmed Phylogenetic and recombination analysis of coronavirus HKU1, a novel coronavirus from patients with pneumonia
title_short Phylogenetic and recombination analysis of coronavirus HKU1, a novel coronavirus from patients with pneumonia
title_sort phylogenetic and recombination analysis of coronavirus hku1, a novel coronavirus from patients with pneumonia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086700/
https://www.ncbi.nlm.nih.gov/pubmed/15986174
http://dx.doi.org/10.1007/s00705-005-0573-2
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