Complete genome analysis of equine coronavirus isolated in Japan

Equine coronavirus has been responsible for several outbreaks of disease in the United States and Japan. Only one complete genome sequence (NC99 isolated in the US) had been reported for this pathogenic RNA virus. Here, we report the complete genome sequences of three equine coronaviruses isolated i...

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Detalles Bibliográficos
Autores principales: Nemoto, Manabu, Oue, Yasuhiro, Murakami, Satoshi, Kanno, Toru, Bannai, Hiroshi, Tsujimura, Koji, Yamanaka, Takashi, Kondo, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2015
Materias:
Annotated Sequence Record
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086706/
https://www.ncbi.nlm.nih.gov/pubmed/26271151
http://dx.doi.org/10.1007/s00705-015-2565-1
Descripción
Sumario:Equine coronavirus has been responsible for several outbreaks of disease in the United States and Japan. Only one complete genome sequence (NC99 isolated in the US) had been reported for this pathogenic RNA virus. Here, we report the complete genome sequences of three equine coronaviruses isolated in 2009 and 2012 in Japan. The genome sequences of Tokachi09, Obihiro12-1 and Obihiro12-2 were 30,782, 30,916 and 30,916 nucleotides in length, respectively, excluding the 3’-poly (A) tails. All three isolates were genetically similar to NC99 (98.2–98.7 %), but deletions and insertions were observed in the genes nsp3 of ORF1a, NS2 and p4.7. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00705-015-2565-1) contains supplementary material, which is available to authorized users.

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