Rat coronavirus (RCV): A prevalent, naturally occurring pneumotropic virus of rats

A new virus isolated from the lungs of rats is prevalent in colony reared and wild rats and induces a fatal pneumonitis in newborn rats. The virus, designated as rat coronavirus (RCV), exhibits properties representative of the coronavirus group: characteristic surface structure, particles somewhat v...

Descripción completa

Detalles Bibliográficos
Autores principales: Parker, J. C., Cross, S. S., Rowe, W. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 1970
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086756/
https://www.ncbi.nlm.nih.gov/pubmed/4099196
http://dx.doi.org/10.1007/BF01253764
_version_ 1783509189822251008
author Parker, J. C.
Cross, S. S.
Rowe, W. P.
author_facet Parker, J. C.
Cross, S. S.
Rowe, W. P.
author_sort Parker, J. C.
collection PubMed
description A new virus isolated from the lungs of rats is prevalent in colony reared and wild rats and induces a fatal pneumonitis in newborn rats. The virus, designated as rat coronavirus (RCV), exhibits properties representative of the coronavirus group: characteristic surface structure, particles somewhat variable in size averaging approximately 90 mμ, apparent RNA content, essential lipid, heat sensitivity, and a close serologie relationship with the mouse hepatitis virus complex. RCV grows well in primary rat kidney cell cultures, exhibits a pathognomonic type CPE, and produces a complement fixing antigen which is sensitive for detection of antibody and useful in sero-epidemiologic studies.
format Online
Article
Text
id pubmed-7086756
institution National Center for Biotechnology Information
language English
publishDate 1970
publisher Springer-Verlag
record_format MEDLINE/PubMed
spelling pubmed-70867562020-03-23 Rat coronavirus (RCV): A prevalent, naturally occurring pneumotropic virus of rats Parker, J. C. Cross, S. S. Rowe, W. P. Arch Gesamte Virusforsch Article A new virus isolated from the lungs of rats is prevalent in colony reared and wild rats and induces a fatal pneumonitis in newborn rats. The virus, designated as rat coronavirus (RCV), exhibits properties representative of the coronavirus group: characteristic surface structure, particles somewhat variable in size averaging approximately 90 mμ, apparent RNA content, essential lipid, heat sensitivity, and a close serologie relationship with the mouse hepatitis virus complex. RCV grows well in primary rat kidney cell cultures, exhibits a pathognomonic type CPE, and produces a complement fixing antigen which is sensitive for detection of antibody and useful in sero-epidemiologic studies. Springer-Verlag 1970 /pmc/articles/PMC7086756/ /pubmed/4099196 http://dx.doi.org/10.1007/BF01253764 Text en © Springer-Verlag 1970 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Parker, J. C.
Cross, S. S.
Rowe, W. P.
Rat coronavirus (RCV): A prevalent, naturally occurring pneumotropic virus of rats
title Rat coronavirus (RCV): A prevalent, naturally occurring pneumotropic virus of rats
title_full Rat coronavirus (RCV): A prevalent, naturally occurring pneumotropic virus of rats
title_fullStr Rat coronavirus (RCV): A prevalent, naturally occurring pneumotropic virus of rats
title_full_unstemmed Rat coronavirus (RCV): A prevalent, naturally occurring pneumotropic virus of rats
title_short Rat coronavirus (RCV): A prevalent, naturally occurring pneumotropic virus of rats
title_sort rat coronavirus (rcv): a prevalent, naturally occurring pneumotropic virus of rats
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086756/
https://www.ncbi.nlm.nih.gov/pubmed/4099196
http://dx.doi.org/10.1007/BF01253764
work_keys_str_mv AT parkerjc ratcoronavirusrcvaprevalentnaturallyoccurringpneumotropicvirusofrats
AT crossss ratcoronavirusrcvaprevalentnaturallyoccurringpneumotropicvirusofrats
AT rowewp ratcoronavirusrcvaprevalentnaturallyoccurringpneumotropicvirusofrats

Ejemplares similares