Specific tropism of Japanese encephalitis virus for developing neurons in primary rat brain culture

Among all the neural cells in fetal rat brain culture developing neurons showed the highest rate of infection by Japanese encephalitis virus (JEV). JEV specifically bound to these cells as measured by immuno-staining. These results indicate that developing neurons are the major target of JEV, and th...

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Detalles Bibliográficos
Autores principales: Kimura-Kuroda, J., Ichikawa, M., Ogata, A., Nagashima, K., Yasui, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 1993
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086854/
https://www.ncbi.nlm.nih.gov/pubmed/8517798
http://dx.doi.org/10.1007/BF01309676
Descripción
Sumario:Among all the neural cells in fetal rat brain culture developing neurons showed the highest rate of infection by Japanese encephalitis virus (JEV). JEV specifically bound to these cells as measured by immuno-staining. These results indicate that developing neurons are the major target of JEV, and that the initial specific binding of virus to these cells may be one of the reasons for the neurotropism of JEV.

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