Specific tropism of Japanese encephalitis virus for developing neurons in primary rat brain culture

Among all the neural cells in fetal rat brain culture developing neurons showed the highest rate of infection by Japanese encephalitis virus (JEV). JEV specifically bound to these cells as measured by immuno-staining. These results indicate that developing neurons are the major target of JEV, and th...

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Detalles Bibliográficos
Autores principales: Kimura-Kuroda, J., Ichikawa, M., Ogata, A., Nagashima, K., Yasui, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 1993
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086854/
https://www.ncbi.nlm.nih.gov/pubmed/8517798
http://dx.doi.org/10.1007/BF01309676
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author Kimura-Kuroda, J.
Ichikawa, M.
Ogata, A.
Nagashima, K.
Yasui, K.
author_facet Kimura-Kuroda, J.
Ichikawa, M.
Ogata, A.
Nagashima, K.
Yasui, K.
author_sort Kimura-Kuroda, J.
collection PubMed
description Among all the neural cells in fetal rat brain culture developing neurons showed the highest rate of infection by Japanese encephalitis virus (JEV). JEV specifically bound to these cells as measured by immuno-staining. These results indicate that developing neurons are the major target of JEV, and that the initial specific binding of virus to these cells may be one of the reasons for the neurotropism of JEV.
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spelling pubmed-70868542020-03-23 Specific tropism of Japanese encephalitis virus for developing neurons in primary rat brain culture Kimura-Kuroda, J. Ichikawa, M. Ogata, A. Nagashima, K. Yasui, K. Arch Virol Brief Report Among all the neural cells in fetal rat brain culture developing neurons showed the highest rate of infection by Japanese encephalitis virus (JEV). JEV specifically bound to these cells as measured by immuno-staining. These results indicate that developing neurons are the major target of JEV, and that the initial specific binding of virus to these cells may be one of the reasons for the neurotropism of JEV. Springer-Verlag 1993 /pmc/articles/PMC7086854/ /pubmed/8517798 http://dx.doi.org/10.1007/BF01309676 Text en © Springer-Verlag 1993 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Brief Report
Kimura-Kuroda, J.
Ichikawa, M.
Ogata, A.
Nagashima, K.
Yasui, K.
Specific tropism of Japanese encephalitis virus for developing neurons in primary rat brain culture
title Specific tropism of Japanese encephalitis virus for developing neurons in primary rat brain culture
title_full Specific tropism of Japanese encephalitis virus for developing neurons in primary rat brain culture
title_fullStr Specific tropism of Japanese encephalitis virus for developing neurons in primary rat brain culture
title_full_unstemmed Specific tropism of Japanese encephalitis virus for developing neurons in primary rat brain culture
title_short Specific tropism of Japanese encephalitis virus for developing neurons in primary rat brain culture
title_sort specific tropism of japanese encephalitis virus for developing neurons in primary rat brain culture
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086854/
https://www.ncbi.nlm.nih.gov/pubmed/8517798
http://dx.doi.org/10.1007/BF01309676
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