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A comparative analysis of measles virus RNA by oligonucleotide fingerprinting
Isolates from two cases of acute measles, one case of acute measles encephalitis and three patients with subacute sclerosing panencephalitis were compared. This comparison was based upon the electrophoretic analysis of T(1) oligonucleotides from single-stranded, full-length RNA isolated from cytopla...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
1982
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086895/ https://www.ncbi.nlm.nih.gov/pubmed/7092572 http://dx.doi.org/10.1007/BF01315058 |
| Sumario: | Isolates from two cases of acute measles, one case of acute measles encephalitis and three patients with subacute sclerosing panencephalitis were compared. This comparison was based upon the electrophoretic analysis of T(1) oligonucleotides from single-stranded, full-length RNA isolated from cytoplasmic nucleocapsids. Although all viruses have oligonucleotides in common, each isolate generated a unique pattern of oligonucleotides. However, no group of oligonucleotides was observed which would allow a differentiation between viruses isolated from acute infections and those isolated from CNS diseases; indicating that probably all measles viruses differ in their nucleotide sequence, regardless of origin. |
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