A comparative analysis of measles virus RNA by oligonucleotide fingerprinting

Isolates from two cases of acute measles, one case of acute measles encephalitis and three patients with subacute sclerosing panencephalitis were compared. This comparison was based upon the electrophoretic analysis of T(1) oligonucleotides from single-stranded, full-length RNA isolated from cytopla...

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Detalles Bibliográficos
Autores principales: Stephenson, J. R., ter Meulen, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 1982
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086895/
https://www.ncbi.nlm.nih.gov/pubmed/7092572
http://dx.doi.org/10.1007/BF01315058
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author Stephenson, J. R.
ter Meulen, V.
author_facet Stephenson, J. R.
ter Meulen, V.
author_sort Stephenson, J. R.
collection PubMed
description Isolates from two cases of acute measles, one case of acute measles encephalitis and three patients with subacute sclerosing panencephalitis were compared. This comparison was based upon the electrophoretic analysis of T(1) oligonucleotides from single-stranded, full-length RNA isolated from cytoplasmic nucleocapsids. Although all viruses have oligonucleotides in common, each isolate generated a unique pattern of oligonucleotides. However, no group of oligonucleotides was observed which would allow a differentiation between viruses isolated from acute infections and those isolated from CNS diseases; indicating that probably all measles viruses differ in their nucleotide sequence, regardless of origin.
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spelling pubmed-70868952020-03-23 A comparative analysis of measles virus RNA by oligonucleotide fingerprinting Stephenson, J. R. ter Meulen, V. Arch Virol Original Papers Isolates from two cases of acute measles, one case of acute measles encephalitis and three patients with subacute sclerosing panencephalitis were compared. This comparison was based upon the electrophoretic analysis of T(1) oligonucleotides from single-stranded, full-length RNA isolated from cytoplasmic nucleocapsids. Although all viruses have oligonucleotides in common, each isolate generated a unique pattern of oligonucleotides. However, no group of oligonucleotides was observed which would allow a differentiation between viruses isolated from acute infections and those isolated from CNS diseases; indicating that probably all measles viruses differ in their nucleotide sequence, regardless of origin. Springer-Verlag 1982 /pmc/articles/PMC7086895/ /pubmed/7092572 http://dx.doi.org/10.1007/BF01315058 Text en © Springer-Verlag 1982 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Papers
Stephenson, J. R.
ter Meulen, V.
A comparative analysis of measles virus RNA by oligonucleotide fingerprinting
title A comparative analysis of measles virus RNA by oligonucleotide fingerprinting
title_full A comparative analysis of measles virus RNA by oligonucleotide fingerprinting
title_fullStr A comparative analysis of measles virus RNA by oligonucleotide fingerprinting
title_full_unstemmed A comparative analysis of measles virus RNA by oligonucleotide fingerprinting
title_short A comparative analysis of measles virus RNA by oligonucleotide fingerprinting
title_sort comparative analysis of measles virus rna by oligonucleotide fingerprinting
topic Original Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086895/
https://www.ncbi.nlm.nih.gov/pubmed/7092572
http://dx.doi.org/10.1007/BF01315058
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