Cargando…

Antigenic relationships amongst coronaviruses

Several serological interrelationships between various members of the corona-virus group have been revealed in neutralization, complement fixation, and gel-diffusion tests, using human and hyperimmune animal sera. Several members of this group of human and animal pathogens are shown to cross-react i...

Descripción completa

Detalles Bibliográficos
Autor principal: Bradburne, A. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 1970
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086994/
https://www.ncbi.nlm.nih.gov/pubmed/4321451
http://dx.doi.org/10.1007/BF01253769
_version_ 1783509243377221632
author Bradburne, A. F.
author_facet Bradburne, A. F.
author_sort Bradburne, A. F.
collection PubMed
description Several serological interrelationships between various members of the corona-virus group have been revealed in neutralization, complement fixation, and gel-diffusion tests, using human and hyperimmune animal sera. Several members of this group of human and animal pathogens are shown to cross-react in one or more type of test, but one member, avian infectious bronchitis virus, was shown to be unrelated. Mouse hepatitis virus (MHV(3)) was found to be antigenically related to a number of human types of coronavirus. Difficulties were encountered in the investigation of paired human sera in demonstrating the specificity of antibody rises, placing doubt on the values of some serological studies. The significance of these interrelationships is discussed in the light of other investigations.
format Online
Article
Text
id pubmed-7086994
institution National Center for Biotechnology Information
language English
publishDate 1970
publisher Springer-Verlag
record_format MEDLINE/PubMed
spelling pubmed-70869942020-03-23 Antigenic relationships amongst coronaviruses Bradburne, A. F. Arch Gesamte Virusforsch Article Several serological interrelationships between various members of the corona-virus group have been revealed in neutralization, complement fixation, and gel-diffusion tests, using human and hyperimmune animal sera. Several members of this group of human and animal pathogens are shown to cross-react in one or more type of test, but one member, avian infectious bronchitis virus, was shown to be unrelated. Mouse hepatitis virus (MHV(3)) was found to be antigenically related to a number of human types of coronavirus. Difficulties were encountered in the investigation of paired human sera in demonstrating the specificity of antibody rises, placing doubt on the values of some serological studies. The significance of these interrelationships is discussed in the light of other investigations. Springer-Verlag 1970 /pmc/articles/PMC7086994/ /pubmed/4321451 http://dx.doi.org/10.1007/BF01253769 Text en © Springer-Verlag 1970 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Bradburne, A. F.
Antigenic relationships amongst coronaviruses
title Antigenic relationships amongst coronaviruses
title_full Antigenic relationships amongst coronaviruses
title_fullStr Antigenic relationships amongst coronaviruses
title_full_unstemmed Antigenic relationships amongst coronaviruses
title_short Antigenic relationships amongst coronaviruses
title_sort antigenic relationships amongst coronaviruses
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086994/
https://www.ncbi.nlm.nih.gov/pubmed/4321451
http://dx.doi.org/10.1007/BF01253769
work_keys_str_mv AT bradburneaf antigenicrelationshipsamongstcoronaviruses