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Biological and pathological consequences of feline infectious peritonitis virus infection in the cheetah
An epizootic of feline infectious peritonitis in a captive cheetah population during 1982–1983 served to focus attention on the susceptibility of the cheetah (Acinoyx jubatus) to infectious disease. Subsequent observations based upon seroepidemiological surveys and electron microscopy of fecal mater...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
1988
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087010/ https://www.ncbi.nlm.nih.gov/pubmed/2849387 http://dx.doi.org/10.1007/BF01310822 |
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author | Evermann, J. F. Heeney, J. L. Roelke, M. E. McKeirnan, A. J. O'Brien, S. J. |
author_facet | Evermann, J. F. Heeney, J. L. Roelke, M. E. McKeirnan, A. J. O'Brien, S. J. |
author_sort | Evermann, J. F. |
collection | PubMed |
description | An epizootic of feline infectious peritonitis in a captive cheetah population during 1982–1983 served to focus attention on the susceptibility of the cheetah (Acinoyx jubatus) to infectious disease. Subsequent observations based upon seroepidemiological surveys and electron microscopy of fecal material verified that cheetahs were indeed capable of being infected by coronaviruses, which were antigenically related to coronaviruses affecting domestic cats, i.e. feline infectious peritonitis virus/feline enteric coronavirus. Coincident with the apparent increased susceptibility of the cheetah to infectious diseases, were observations that the cheetah was genetically unusual insofar as large amounts of enzyme-encoding loci were monomorphic, and that unrelated cheetahs were capable of accepting allogenic skin grafts. These data provided the basis for a hypothesis that the cheetah, through intensive inbreeding, had become more susceptible to viral infections as a result of genetic homogeneity. |
format | Online Article Text |
id | pubmed-7087010 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1988 |
publisher | Springer-Verlag |
record_format | MEDLINE/PubMed |
spelling | pubmed-70870102020-03-23 Biological and pathological consequences of feline infectious peritonitis virus infection in the cheetah Evermann, J. F. Heeney, J. L. Roelke, M. E. McKeirnan, A. J. O'Brien, S. J. Arch Virol Brief Review An epizootic of feline infectious peritonitis in a captive cheetah population during 1982–1983 served to focus attention on the susceptibility of the cheetah (Acinoyx jubatus) to infectious disease. Subsequent observations based upon seroepidemiological surveys and electron microscopy of fecal material verified that cheetahs were indeed capable of being infected by coronaviruses, which were antigenically related to coronaviruses affecting domestic cats, i.e. feline infectious peritonitis virus/feline enteric coronavirus. Coincident with the apparent increased susceptibility of the cheetah to infectious diseases, were observations that the cheetah was genetically unusual insofar as large amounts of enzyme-encoding loci were monomorphic, and that unrelated cheetahs were capable of accepting allogenic skin grafts. These data provided the basis for a hypothesis that the cheetah, through intensive inbreeding, had become more susceptible to viral infections as a result of genetic homogeneity. Springer-Verlag 1988 /pmc/articles/PMC7087010/ /pubmed/2849387 http://dx.doi.org/10.1007/BF01310822 Text en © Springer-Verlag 1988 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Brief Review Evermann, J. F. Heeney, J. L. Roelke, M. E. McKeirnan, A. J. O'Brien, S. J. Biological and pathological consequences of feline infectious peritonitis virus infection in the cheetah |
title | Biological and pathological consequences of feline infectious peritonitis virus infection in the cheetah |
title_full | Biological and pathological consequences of feline infectious peritonitis virus infection in the cheetah |
title_fullStr | Biological and pathological consequences of feline infectious peritonitis virus infection in the cheetah |
title_full_unstemmed | Biological and pathological consequences of feline infectious peritonitis virus infection in the cheetah |
title_short | Biological and pathological consequences of feline infectious peritonitis virus infection in the cheetah |
title_sort | biological and pathological consequences of feline infectious peritonitis virus infection in the cheetah |
topic | Brief Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087010/ https://www.ncbi.nlm.nih.gov/pubmed/2849387 http://dx.doi.org/10.1007/BF01310822 |
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