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Molecular detection and characterization of human gyroviruses identified in the ferret fecal virome
The recently described novel gyroviruses may infect chickens and/or humans; however, their pathogenic potential is unknown. In our metagenomic investigation, we detected many of the novel gyroviruses in the fecal viromes of ferrets with lymph node and organ enlargement. The complete genomic sequence...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087032/ https://www.ncbi.nlm.nih.gov/pubmed/25119678 http://dx.doi.org/10.1007/s00705-014-2203-3 |
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author | Fehér, Enikő Pazár, Péter Kovács, Eszter Farkas, Szilvia L. Lengyel, György Jakab, Ferenc Martella, Vito Bányai, Krisztián |
author_facet | Fehér, Enikő Pazár, Péter Kovács, Eszter Farkas, Szilvia L. Lengyel, György Jakab, Ferenc Martella, Vito Bányai, Krisztián |
author_sort | Fehér, Enikő |
collection | PubMed |
description | The recently described novel gyroviruses may infect chickens and/or humans; however, their pathogenic potential is unknown. In our metagenomic investigation, we detected many of the novel gyroviruses in the fecal viromes of ferrets with lymph node and organ enlargement. The complete genomic sequences of selected gyrovirus strains showed 90.7-99.4 % similarity to homologous reference gyrovirus strains. This study did not demonstrate an association between gyrovirus shedding from ferrets and the observed background disease; however, it provides evidence for genetic diversity among gyroviruses and raises the possibility that pet ferrets may transmit gyroviruses to heterologous hosts, e.g., humans. |
format | Online Article Text |
id | pubmed-7087032 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Springer Vienna |
record_format | MEDLINE/PubMed |
spelling | pubmed-70870322020-03-23 Molecular detection and characterization of human gyroviruses identified in the ferret fecal virome Fehér, Enikő Pazár, Péter Kovács, Eszter Farkas, Szilvia L. Lengyel, György Jakab, Ferenc Martella, Vito Bányai, Krisztián Arch Virol Brief Report The recently described novel gyroviruses may infect chickens and/or humans; however, their pathogenic potential is unknown. In our metagenomic investigation, we detected many of the novel gyroviruses in the fecal viromes of ferrets with lymph node and organ enlargement. The complete genomic sequences of selected gyrovirus strains showed 90.7-99.4 % similarity to homologous reference gyrovirus strains. This study did not demonstrate an association between gyrovirus shedding from ferrets and the observed background disease; however, it provides evidence for genetic diversity among gyroviruses and raises the possibility that pet ferrets may transmit gyroviruses to heterologous hosts, e.g., humans. Springer Vienna 2014-08-14 2014 /pmc/articles/PMC7087032/ /pubmed/25119678 http://dx.doi.org/10.1007/s00705-014-2203-3 Text en © Springer-Verlag Wien 2014 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Brief Report Fehér, Enikő Pazár, Péter Kovács, Eszter Farkas, Szilvia L. Lengyel, György Jakab, Ferenc Martella, Vito Bányai, Krisztián Molecular detection and characterization of human gyroviruses identified in the ferret fecal virome |
title | Molecular detection and characterization of human gyroviruses identified in the ferret fecal virome |
title_full | Molecular detection and characterization of human gyroviruses identified in the ferret fecal virome |
title_fullStr | Molecular detection and characterization of human gyroviruses identified in the ferret fecal virome |
title_full_unstemmed | Molecular detection and characterization of human gyroviruses identified in the ferret fecal virome |
title_short | Molecular detection and characterization of human gyroviruses identified in the ferret fecal virome |
title_sort | molecular detection and characterization of human gyroviruses identified in the ferret fecal virome |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087032/ https://www.ncbi.nlm.nih.gov/pubmed/25119678 http://dx.doi.org/10.1007/s00705-014-2203-3 |
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