Growth of mouse hepatitis and other indigenous mouse viruses in tracheal organ cultures

Organ cultures of mouse trachea were infected with some indigenous mouse viruses. Mengovirus and reovirus type 3 grew to high titer; inocula of, respectively, 10(2) and 10(3) TCID(50) were required to initiate infection. Organ cultures supported also the growth of mouse hepatitis viruses, MHV-3 and...

Descripción completa

Detalles Bibliográficos
Autores principales: Maase, E., van der Veen, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 1974
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087086/
https://www.ncbi.nlm.nih.gov/pubmed/4368757
http://dx.doi.org/10.1007/BF01251020
_version_ 1783509263133442048
author Maase, E.
van der Veen, J.
author_facet Maase, E.
van der Veen, J.
author_sort Maase, E.
collection PubMed
description Organ cultures of mouse trachea were infected with some indigenous mouse viruses. Mengovirus and reovirus type 3 grew to high titer; inocula of, respectively, 10(2) and 10(3) TCID(50) were required to initiate infection. Organ cultures supported also the growth of mouse hepatitis viruses, MHV-3 and MHV-S, though to a lesser extent. Viral production was noted for periods of as long as two weeks. None of the viruses had a noticeable effect on the ciliary activity or acquired such capacity on serial passage in organ cultures.
format Online
Article
Text
id pubmed-7087086
institution National Center for Biotechnology Information
language English
publishDate 1974
publisher Springer-Verlag
record_format MEDLINE/PubMed
spelling pubmed-70870862020-03-23 Growth of mouse hepatitis and other indigenous mouse viruses in tracheal organ cultures Maase, E. van der Veen, J. Arch Gesamte Virusforsch Article Organ cultures of mouse trachea were infected with some indigenous mouse viruses. Mengovirus and reovirus type 3 grew to high titer; inocula of, respectively, 10(2) and 10(3) TCID(50) were required to initiate infection. Organ cultures supported also the growth of mouse hepatitis viruses, MHV-3 and MHV-S, though to a lesser extent. Viral production was noted for periods of as long as two weeks. None of the viruses had a noticeable effect on the ciliary activity or acquired such capacity on serial passage in organ cultures. Springer-Verlag 1974 /pmc/articles/PMC7087086/ /pubmed/4368757 http://dx.doi.org/10.1007/BF01251020 Text en © Springer-Verlag 1974 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Maase, E.
van der Veen, J.
Growth of mouse hepatitis and other indigenous mouse viruses in tracheal organ cultures
title Growth of mouse hepatitis and other indigenous mouse viruses in tracheal organ cultures
title_full Growth of mouse hepatitis and other indigenous mouse viruses in tracheal organ cultures
title_fullStr Growth of mouse hepatitis and other indigenous mouse viruses in tracheal organ cultures
title_full_unstemmed Growth of mouse hepatitis and other indigenous mouse viruses in tracheal organ cultures
title_short Growth of mouse hepatitis and other indigenous mouse viruses in tracheal organ cultures
title_sort growth of mouse hepatitis and other indigenous mouse viruses in tracheal organ cultures
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087086/
https://www.ncbi.nlm.nih.gov/pubmed/4368757
http://dx.doi.org/10.1007/BF01251020
work_keys_str_mv AT maasee growthofmousehepatitisandotherindigenousmousevirusesintrachealorgancultures
AT vanderveenj growthofmousehepatitisandotherindigenousmousevirusesintrachealorgancultures

Ejemplares similares