Inhibition of the PI3K/Akt pathway by Ly294002 does not prevent establishment of persistent Junín virus infection in Vero cells

In previous work, we demonstrated that the arenavirus Junín virus (JUNV) is able to activate Akt by means of the phosphatidylinositol-3-kinase (PI3K) survival pathway during virus entry. This work extends our study, emphasizing the relevance of this pathway in the establishment and maintenance of pe...

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Detalles Bibliográficos
Autores principales: Linero, Florencia N., Fernández Bell-Fano, Pablo M., Cuervo, Eugenia, Castilla, Viviana, Scolaro, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2014
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087115/
https://www.ncbi.nlm.nih.gov/pubmed/25488290
http://dx.doi.org/10.1007/s00705-014-2298-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087115/
https://www.ncbi.nlm.nih.gov/pubmed/25488290
http://dx.doi.org/10.1007/s00705-014-2298-6

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