Requirements for empirical immunogenicity trials, rather than structure-based design, for developing an effective HIV vaccine

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The claim that it is possible to rationally design a structure-based HIV-1 vaccine is based on misconceptions regarding the nature of protein epitopes and of immunological specificity. Attempts to use reverse vaccinology to generate an HIV-1 vaccine on the basis of the structure of viral epitopes bo...

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Detalles Bibliográficos
Autor principal: Van Regenmortel, Marc H. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2011
Materias:
Brief Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087187/
https://www.ncbi.nlm.nih.gov/pubmed/22012269
http://dx.doi.org/10.1007/s00705-011-1145-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087187/
https://www.ncbi.nlm.nih.gov/pubmed/22012269
http://dx.doi.org/10.1007/s00705-011-1145-2

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