Serum interferon assay as a possible test for virus infections of man

Acute phase serum gave positive results in an interferon assay when collected from 17 out of 45 (38 per cent) patients with proven virus infection, and from none of 43 patients with other disease and none of 61 healthy subjects. Sera from 11 of 43 (26 per cent) patients with suspected virus infectio...

Descripción completa

Detalles Bibliográficos
Autores principales: Matthews, T. H. J., Lawrence, M. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 1979
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087210/
https://www.ncbi.nlm.nih.gov/pubmed/426632
http://dx.doi.org/10.1007/BF01317892
_version_ 1783509291321262080
author Matthews, T. H. J.
Lawrence, M. K.
author_facet Matthews, T. H. J.
Lawrence, M. K.
author_sort Matthews, T. H. J.
collection PubMed
description Acute phase serum gave positive results in an interferon assay when collected from 17 out of 45 (38 per cent) patients with proven virus infection, and from none of 43 patients with other disease and none of 61 healthy subjects. Sera from 11 of 43 (26 per cent) patients with suspected virus infection were also positive. Interferon was detected in the sera of volunteers infected with respiratory viruses in strict isolation. It is suggested that the test might be used to supplement conventional tests for virus infections, and with modification may provide a useful diagnostic aid.
format Online
Article
Text
id pubmed-7087210
institution National Center for Biotechnology Information
language English
publishDate 1979
publisher Springer-Verlag
record_format MEDLINE/PubMed
spelling pubmed-70872102020-03-23 Serum interferon assay as a possible test for virus infections of man Matthews, T. H. J. Lawrence, M. K. Arch Virol Original Papers Acute phase serum gave positive results in an interferon assay when collected from 17 out of 45 (38 per cent) patients with proven virus infection, and from none of 43 patients with other disease and none of 61 healthy subjects. Sera from 11 of 43 (26 per cent) patients with suspected virus infection were also positive. Interferon was detected in the sera of volunteers infected with respiratory viruses in strict isolation. It is suggested that the test might be used to supplement conventional tests for virus infections, and with modification may provide a useful diagnostic aid. Springer-Verlag 1979 /pmc/articles/PMC7087210/ /pubmed/426632 http://dx.doi.org/10.1007/BF01317892 Text en © Springer-Verlag 1979 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Papers
Matthews, T. H. J.
Lawrence, M. K.
Serum interferon assay as a possible test for virus infections of man
title Serum interferon assay as a possible test for virus infections of man
title_full Serum interferon assay as a possible test for virus infections of man
title_fullStr Serum interferon assay as a possible test for virus infections of man
title_full_unstemmed Serum interferon assay as a possible test for virus infections of man
title_short Serum interferon assay as a possible test for virus infections of man
title_sort serum interferon assay as a possible test for virus infections of man
topic Original Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087210/
https://www.ncbi.nlm.nih.gov/pubmed/426632
http://dx.doi.org/10.1007/BF01317892
work_keys_str_mv AT matthewsthj seruminterferonassayasapossibletestforvirusinfectionsofman
AT lawrencemk seruminterferonassayasapossibletestforvirusinfectionsofman

Ejemplares similares