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Protective effect of an inactivated avian coronavirus vaccine administered by aerosol
The antigenicity and protective effect of 3 strains of avian infectious bronchitis virus inactivated by beta-propiolactone were studied. Chickens administered 2 doses of the inactivated Connecticut strain (IBV-46) vaccine by aerosol at 3-week intervals had significant levels of virus-neutralizing an...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer-Verlag
1973
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087329/ https://www.ncbi.nlm.nih.gov/pubmed/4716970 http://dx.doi.org/10.1007/BF01249930 |
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author | Coria, M. F. |
author_facet | Coria, M. F. |
author_sort | Coria, M. F. |
collection | PubMed |
description | The antigenicity and protective effect of 3 strains of avian infectious bronchitis virus inactivated by beta-propiolactone were studied. Chickens administered 2 doses of the inactivated Connecticut strain (IBV-46) vaccine by aerosol at 3-week intervals had significant levels of virus-neutralizing antibodies and were resistant to infection by the Massachusetts strain (IBV-41) as determined by virus isolation attempts. Antibody levels in chickens given inactivated Iowa 33 and Iowa 609 were not significant and they were not resistant to infection by IBV-41. |
format | Online Article Text |
id | pubmed-7087329 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1973 |
publisher | Springer-Verlag |
record_format | MEDLINE/PubMed |
spelling | pubmed-70873292020-03-23 Protective effect of an inactivated avian coronavirus vaccine administered by aerosol Coria, M. F. Arch Gesamte Virusforsch Article The antigenicity and protective effect of 3 strains of avian infectious bronchitis virus inactivated by beta-propiolactone were studied. Chickens administered 2 doses of the inactivated Connecticut strain (IBV-46) vaccine by aerosol at 3-week intervals had significant levels of virus-neutralizing antibodies and were resistant to infection by the Massachusetts strain (IBV-41) as determined by virus isolation attempts. Antibody levels in chickens given inactivated Iowa 33 and Iowa 609 were not significant and they were not resistant to infection by IBV-41. Springer-Verlag 1973 /pmc/articles/PMC7087329/ /pubmed/4716970 http://dx.doi.org/10.1007/BF01249930 Text en © Springer-Verlag 1973 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Article Coria, M. F. Protective effect of an inactivated avian coronavirus vaccine administered by aerosol |
title | Protective effect of an inactivated avian coronavirus vaccine administered by aerosol |
title_full | Protective effect of an inactivated avian coronavirus vaccine administered by aerosol |
title_fullStr | Protective effect of an inactivated avian coronavirus vaccine administered by aerosol |
title_full_unstemmed | Protective effect of an inactivated avian coronavirus vaccine administered by aerosol |
title_short | Protective effect of an inactivated avian coronavirus vaccine administered by aerosol |
title_sort | protective effect of an inactivated avian coronavirus vaccine administered by aerosol |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087329/ https://www.ncbi.nlm.nih.gov/pubmed/4716970 http://dx.doi.org/10.1007/BF01249930 |
work_keys_str_mv | AT coriamf protectiveeffectofaninactivatedaviancoronavirusvaccineadministeredbyaerosol |