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Tumor necrosis factor inhibition attenuates white matter gliosis after systemic inflammation in preterm fetal sheep

BACKGROUND: Increased circulating levels of tumor necrosis factor (TNF) are associated with greater risk of impaired neurodevelopment after preterm birth. In this study, we tested the hypothesis that systemic TNF inhibition, using the soluble TNF receptor Etanercept, would attenuate neuroinflammatio...

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Detalles Bibliográficos
Autores principales: Galinsky, Robert, Dhillon, Simerdeep K., Dean, Justin M., Davidson, Joanne O., Lear, Christopher A., Wassink, Guido, Nott, Fraser, Kelly, Sharmony B., Fraser, Mhoyra, Yuill, Caroline, Bennet, Laura, Gunn, Alistair Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087378/
https://www.ncbi.nlm.nih.gov/pubmed/32293473
http://dx.doi.org/10.1186/s12974-020-01769-6

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