Obstacles to detecting isoforms using full-length scRNA-seq data

BACKGROUND: Early single-cell RNA-seq (scRNA-seq) studies suggested that it was unusual to see more than one isoform being produced from a gene in a single cell, even when multiple isoforms were detected in matched bulk RNA-seq samples. However, these studies generally did not consider the impact of...

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Detalles Bibliográficos
Autores principales: Westoby, Jennifer, Artemov, Pavel, Hemberg, Martin, Ferguson-Smith, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087381/
https://www.ncbi.nlm.nih.gov/pubmed/32293520
http://dx.doi.org/10.1186/s13059-020-01981-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087381/
https://www.ncbi.nlm.nih.gov/pubmed/32293520
http://dx.doi.org/10.1186/s13059-020-01981-w

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