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Clinical-grade cryopreserved doxorubicin-loaded platelets: role of cancer cells and platelet extracellular vesicles activation loop

BACKGROUND: Human platelets (PLT) and PLT-extracellular vesicles (PEV) released upon thrombin activation express receptors that interact with tumour cells and, thus, can serve as a delivery platform of anti-cancer agents. Drug-loaded nanoparticles coated with PLT membranes were demonstrated to have...

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Detalles Bibliográficos
Autores principales:	Wu, Yu-Wen, Huang, Cheng-Chain, Changou, Chun Austin, Lu, Long-Sheng, Goubran, Hadi, Burnouf, Thierry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087392/ https://www.ncbi.nlm.nih.gov/pubmed/32200762 http://dx.doi.org/10.1186/s12929-020-00633-2

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